Evidence map›Paper›PMID 38913541›Full record

ArticleGut microbes

Gut microbial features and dietary fiber intake predict gut microbiota response to resistant starch supplementation.

Sri Lakshmi Sravani Devarakonda, Dorothy K Superdock, Jennifer Ren, Lynn M Johnson, Aura Alex P Loinard-González, Angela C Poole

Abstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  6. Short-chain fatty acids.Nature metabolism · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Sri Lakshmi Sravani DevarakondaDivision of Nutritional Sciences, Cornell University, Ithaca, NY, USA.ORCID 0000-0001-8758-7227
Dorothy K SuperdockDivision of Nutritional Sciences, Cornell University, Ithaca, NY, USA.ORCID 0000-0001-5348-3307
Jennifer RenDivision of Nutritional Sciences, Cornell University, Ithaca, NY, USA.
Lynn M JohnsonCornell Statistical Consulting Unit, Cornell University, Ithaca, NY, USA.ORCID 0000-0002-9317-4637
Aura Alex P Loinard-GonzálezDivision of Nutritional Sciences, Cornell University, Ithaca, NY, USA.
Angela C PooleDivision of Nutritional Sciences, Cornell University, Ithaca, NY, USA.ORCID 0000-0003-0278-7655

Funding

TRANSGENIC AND CHIMERIC MOUSE COREP30DK050306 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI REBECCA G WELLS · 1997 to 2026
$32.5M
NUTRITION TRAININGT32DK007158 · NIDDK · CORNELL UNIVERSITY ITHACA · PI PATRICIA A CASSANO, Julia L. Finkelstein · 1986 to 2026
$7.4M
NIDDK NIH HHS P30 DK050306NIDDK NIH HHS T32 DK007158
6 · The paper itself

Abstract

Resistant starch (RS) consumption can have beneficial effects on metabolic health, but the response, in terms of effects on the gut microbiota and host physiology, varies between individuals. Factors predicting the response to RS are not yet established and would be useful for developing precision nutrition approaches that maximize the benefits of dietary fiber intake. We sought to identify predictors of gut microbiota response to RS supplementation. We enrolled 76 healthy adults into a 7-week crossover study with 59 individuals completing the study. Participants consumed RS type 2 (RS2), RS type 4 (RS4), and digestible starch, for 10 d each with 5-d washout periods in between. We collected fecal and saliva samples and food records during each treatment period. We performed 16S rRNA gene sequencing and measured fecal short-chain fatty acids (SCFAs), salivary amylase (

Indexed as

BacteriaCross-Over StudiesDietary FiberDietary SupplementsFatty Acids, VolatileFecesGastrointestinal MicrobiomeRNA, Ribosomal, 16SSalivaStarchAdultFemaleHumansMaleMiddle AgedResistant StarchDietary FiberFatty Acids, VolatileResistant StarchRNA, Ribosomal, 16SStarchAMY1amylasedietary fibergut microbiomegut microbiotainterindividualprecision nutritionresistant starchshort-chain fatty acid

Identifiers

PMID38913541
PMCPMC11197919

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.