Evidence map›Paper›PMID 38913422›Full record

ArticleeLife2024

Mapping the molecular motions of 5-HT

Laurie Peverini, Sophie Shi, Karima Medjebeur, Pierre-Jean Corringer

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Hidden complexity of α7 nicotinic acetylcholine receptor desensitization revealed by MD simulations and Markov state modeling.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Laurie PeveriniInstitut Pasteur, Université Paris Cité, CNRS UMR 3571, Channel-Receptors Unit, Paris, France.ORCID https://orcid.org/0000-0002-7992-1245
Sophie ShiInstitut Pasteur, Université Paris Cité, CNRS UMR 3571, Channel-Receptors Unit, Paris, France.
Karima MedjebeurInstitut Pasteur, Université Paris Cité, CNRS UMR 3571, Channel-Receptors Unit, Paris, France.
Pierre-Jean CorringerInstitut Pasteur, Université Paris Cité, CNRS UMR 3571, Channel-Receptors Unit, Paris, France.ORCID https://orcid.org/0000-0002-4770-430X

Funding

European Research Council 788974
6 · The paper itself

Abstract

The serotonin-gated ion channel (5-HT

Indexed as

FluorometryPatch-Clamp TechniquesProtein ConformationReceptors, Serotonin, 5-HT3Binding SitesCryoelectron MicroscopyHEK293 CellsHumansIon Channel GatingSerotoninReceptors, Serotonin, 5-HT3Serotonin5-HT3 receptorsallosteric mechanismsbiochemistrychemical biologymouseneuropharmacologyvoltage-clamp fluorometry

Identifiers

PMID38913422
PMCPMC11196107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.