Evidence map›Paper›PMID 38913308›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2024

Cancer Sample Analysis Utilizing Single-Nucleotide Polymorphism Array and Array Comparative Genomic Hybridization.

Benjamin Kang, Hong Xiao, Todd Ackley, Lina Shao

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Benjamin KangDepartment of Pathology and Pediatrics, University of Michigan, Ann Arbor, MI, USA.
Hong XiaoDepartment of Pathology, University of Michigan, Ann Arbor, MI, USA.
Todd AckleyDepartment of Pathology, University of Michigan, Ann Arbor, MI, USA.
Lina ShaoDepartment of Pathology and Pediatrics, University of Michigan, Ann Arbor, MI, USA. linashao@med.umich.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chromosomal microarray, including single-nucleotide polymorphism (SNP) array and array comparative genomic hybridization (aCGH), enables the detection of DNA copy-number loss and/or gain associated with unbalanced chromosomal aberrations. In addition, SNP array and aCGH with SNP component also detect copy-neutral loss of heterozygosity (CN-LOH). Here we describe the chromosomal microarray procedure from the sample preparation using extracted DNA to the scanning of the array chip.

Indexed as

Comparative Genomic HybridizationNeoplasmsOligonucleotide Array Sequence AnalysisPolymorphism, Single NucleotideChromosome AberrationsDNA Copy Number VariationsHumansLoss of HeterozygosityArray comparative genomic hybridization (aCGH)Chromosomal microarrayCopy-neutral loss of heterozygosity (CN-LOH)Copy-number abnormality (CNA)Single-nucleotide polymorphism (SNP) array

Identifiers

PMID38913308

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.