Evidence map›Paper›PMID 38913194›Full record

ArticleInternational ophthalmology2024

Visual evoked potentials in patients with congenital color vision deficiency.

Berkay Kızıltaş, Halit Fidancı

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Article in International ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Berkay KızıltaşDepartment of Ophthalmology, University of Health Sciences Adana City Training and Research Hospital, Adana, Turkey. berkaykzlts@gmail.com.ORCID http://orcid.org/0009-0003-2330-0946
Halit FidancıDivision of Clinical Neuropsychology, Department of Neurology, University of Health Sciences Adana City Training and Research Hospital, Adana, Turkey.ORCID http://orcid.org/0000-0001-6573-9090

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimCongenital color vision deficiency (CCVD) is an eye disease characterized by abnormalities in the cone cells in the photoreceptor layer. Visual evoked potentials (VEPs) are electrophysiological tests that physiologically examine the optic nerve, other visual pathways, and the visual cortex. The aim of this research was to determine whether there are VEP abnormalities in CCVD patients.

methodsPatients with CCVD and healthy individuals were included in this prospective case-control study. Participants with eye disease or neurodegenerative disease were excluded from the study. Pattern reversal VEP (PVEP), flash VEP (FVEP), and optical coherence tomography were performed on all participants.

resultsTwenty healthy individuals (15 male) and 21 patients with CCVD (18 male) were included in the study. The mean ages of healthy individuals and patients with CCVD were 29.8 ± 9.6 and 31.1 ± 10.9 years (p = 0.804). Retinal nerve fiber layer thickness and central macular thickness values did not differ between the two groups. In PVEP, Right P100, Left N75, P100, N135 values were delayed in CCVD patients compared to healthy individuals (p = 0.001, p = 0.032, p = 0.003, p = 0.032). At least one PVEP and FVEP abnormality was present in nine (42.9%) and six (28.6%) of the patients, respectively. PVEP or FVEP abnormalities were found in 13 (61.9%) of the patients.

conclusionThis study indicated that there may be PVEP and FVEP abnormalities in patients with CCVD.

Indexed as

Color Vision DefectsEvoked Potentials, VisualTomography, Optical CoherenceAdolescentAdultCase-Control StudiesFemaleHumansMaleMiddle AgedProspective StudiesVisual AcuityYoung AdultColor vision deficiencyRetinal nerve fiber layerVisual evoked potential

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.