Evidence map›Paper›PMID 38913108›Full record

ArticleJournal of assisted reproduction and genetics2024

Modelling and comparing the use of IVF and ICSI in Australia.

Maria Mazi, Georgina James, Peter Temple-Smith, Ben W J Mol

Abstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maria MaziEducation Program in Reproduction and Development, Department of Obstetrics and Gynaecology, School of Clinical Sciences at Monash Health, Monash University, Clayton, 3168, Australia. mariamazis@gmail.com.ORCID http://orcid.org/0000-0002-3671-6436
Georgina JamesEducation Program in Reproduction and Development, Department of Obstetrics and Gynaecology, School of Clinical Sciences at Monash Health, Monash University, Clayton, 3168, Australia.
Peter Temple-SmithEducation Program in Reproduction and Development, Department of Obstetrics and Gynaecology, School of Clinical Sciences at Monash Health, Monash University, Clayton, 3168, Australia.
Ben W J MolEducation Program in Reproduction and Development, Department of Obstetrics and Gynaecology, School of Clinical Sciences at Monash Health, Monash University, Clayton, 3168, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study estimates the need of IVF/ICSI in Australia as compared to its actual uptake.

methodsWe created a model estimating for the annual demand for IVF/ICSI in a hypothetical infertile population, using demographic data from medical literature and Australian government databases. For each category of infertility (tubal, severe male, endometriosis, anovulation and unexplained), our estimated need for IVF/ICSI was compared to the actual IVF/ICSI uptake (ANZARD 2019). The model consisted of three categories depending on couples' cause of infertility, i.e. couples with absolute indications for IVF/ICSI (couples with severe male factor infertility and tubal obstruction); couples with anovulatory infertility (couples with ovulation disorders) and couples with ovulatory infertility (couples suffering from unexplained infertility and endometriosis). The model was applied to each of these categories to determine the number of couples that would require IVF/ICSI treatment after failing to conceive naturally or after following alternative treatment plans. The main outcomes of this study were the estimate of IVF/ICSI cycles and the difference between the estimate and the reported number of IVF/ICSI cycles (2019 ANZARD report).

resultsWe estimated that approximately 35,300 couples required IVF/ICSI treatment in Australia in 2019, while in 2019 according to ANZARD, 46,000 couples underwent IVF/ICSI. A higher uptake of IVF/ICSI cycles than expected was specifically reported in couples with unexplained infertility, ovulation disorders and endometriosis, while for tubal and severe male infertility uptake seemed adequate.

conclusionIn Australia, there seems to be overservicing of IVF/ICSI, specifically for unexplained, ovulatory and endometriosis-related infertility.

Indexed as

Fertilization in VitroSperm Injections, IntracytoplasmicAdultAustraliaFemaleHumansInfertilityMalePregnancyFertility treatmentICSIInfertilityIVFModel populationUnexplained infertility

Identifiers

PMID38913108
PMCPMC11263460

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.