Evidence map›Paper›PMID 38912552›Full record

ReviewDevelopment (Cambridge, England)2024

Historic obstacles and emerging opportunities in the field of developmental metabolism - lessons from Heidelberg.

Alexandra M Garfinkel, Efe Ilker, Hidenobu Miyazawa, Kathrin Schmeisser, Jason M Tennessen

Abstract readReview
In one paragraph

Review in Development (Cambridge, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alexandra M GarfinkelPediatric Genomics Discovery Program, Department of Pediatrics and Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.ORCID 0000-0002-4434-3262
Efe IlkerMax Planck Institute for the Physics of Complex Systems, Dresden 01187, Germany.ORCID 0000-0003-0553-9032
Hidenobu MiyazawaDevelopmental Biology Unit, European Molecular Biology Laboratory, Heidelberg 69117, Germany.ORCID 0000-0001-6164-5134
Kathrin SchmeisserMax Planck Institute of Molecular Cell Biology and Genetics, Dresden 01307, Germany.ORCID 0000-0002-4061-3034
Jason M TennessenDepartment of Biology, Indiana University, Bloomington, IN 47405, USA.ORCID 0000-0002-3527-5683

Funding

DIABETES MELLITUS &DISORDERS OF METABOLISMT32DK007058 · NIDDK · YALE UNIVERSITY · PI SONIA CAPRIO, Kevan C Herold · 1986 to 2026
$9.6M
A Drosophila Model for the Regulation of Aerobic GlycolysisR35GM119557 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI Jason Michael Tennessen · 2016 to 2026
$4.7M
European Research Council 949811H2020 Marie Skłodowska-Curie Actions 664726Japan Society for the Promotion of ScienceNIDDK NIH HHS 5T32DK007058-49NIDDK NIH HHS T32 DK007058NIGMS NIH HHS R35 GM119557NIH HHS 1R35GM119557
6 · The paper itself

Abstract

The field of developmental metabolism is experiencing a technological revolution that is opening entirely new fields of inquiry. Advances in metabolomics, small-molecule sensors, single-cell RNA sequencing and computational modeling present new opportunities for exploring cell-specific and tissue-specific metabolic networks, interorgan metabolic communication, and gene-by-metabolite interactions in time and space. Together, these advances not only present a means by which developmental biologists can tackle questions that have challenged the field for centuries, but also present young scientists with opportunities to define new areas of inquiry. These emerging frontiers of developmental metabolism were at the center of a highly interactive 2023 EMBO workshop 'Developmental metabolism: flows of energy, matter, and information'. Here, we summarize key discussions from this forum, emphasizing modern developmental biology's challenges and opportunities.

Indexed as

Developmental BiologyAnimalsHumansMetabolic Networks and PathwaysMetabolomicsDevelopmental metabolismFRET sensorsMetabolic diseasesMetabolic set-pointsSpatial metabolomicsTheoretical modeling

Identifiers

PMID38912552
PMCPMC11299503

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.