ArticleInternational journal of applied & basic medical research
D-dimer as a Marker of Severity and Prognosis in Acute Pancreatitis.
Article in International journal of applied & basic medical research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- The Diagnostic Value of D-Dimer Testing in the Differential Diagnosis of Acute Abdomen in the Emergency Department.Journal of clinical medicine · 2026Review
- A Narrative Review on Abnormalities in the Hemostatic System in Diabetes Mellitus: Pathophysiology, Clinical Implications, and Therapeutics.Life (Basel, Switzerland) · 2026Review
- Association between peak D-dimer levels within 24 hours of admission and the risk of infected pancreatic necrosis in hyperlipidemic acute pancreatitis: a retrospective analysis.Frontiers in medicine · 2026Article
- Factors Associated with ICU Admission and In-Hospital Mortality in Patients with Acute Pancreatitis: A Single-Center Retrospective Study.Journal of inflammation research · 2026Article
- Advancements in postoperative pancreatic fistula: a comprehensive review of predictive factors, therapies, scoring systems and ongoing trials.eGastroenterology · 2025Review
- Serial D-dimer measurements dynamically predict disease severity in acute biliary pancreatitis: a prospective observational study.Turkish journal of medical sciences · 2025Observational
- Prediction for Acute Biliary Pancreatitis After Laparoscopic Cholecystectomy.Journal of inflammation research · 2025Article
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1 author.
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Abstract
Background and Objectives: Acute pancreatitis (AP) scores need a battery of tests that are not helpful at an early stage. Can a single test predict Complicated Acute Pancreatitis (CAP) which includes moderate and severe AP, local complications, and need for intensive care unit (ICU). Methodology: 30 patients of AP. D-dimer, C-reactive protein levels done within 3 days of AP onset. APACHE II, Ranson's score, CT severity index were done. Inhospital disease course for development of organ failure and need for ICU care was followed daily. Results: D-dimer in CAP was 2732 ng/L (MAP 567 ng/L), in abnormal computed tomography (CT) was 1916 ng/L (normal CT 363 ng/L), and in organ failure was 4776 ng/L (776.5 ng/L absent organ failure). D-dimer increases as the severity of organ failure increases ( Conclusion: Coagulopathy and microthrombi play a significant role in early pathogenesis. D-dimer test acts at the level of this core pathogenesis, even before the complications set in. D-dimer within 72 h of AP correlates well with the CT findings after 72 h. This is the first study that correlates D-dimer levels with CT scores, ICU requirement. D-dimer can guide primary care physicians in selecting AP patients for referral to a higher center in a resource-limited setting.
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