Evidence map›Paper›PMID 38912305›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)

Alexander M Kulminski, Ethan Jain-Washburn, Ian Philipp, Yury Loika, Elena Loiko, Irina Culminskaya

Abstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Alzheimer's & dementia (Amsterdam, Netherlands)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexander M KulminskiBiodemography of Aging Research Unit Social Science Research Institute, Duke University Durham North Carolina USA.
Ethan Jain-WashburnBiodemography of Aging Research Unit Social Science Research Institute, Duke University Durham North Carolina USA.
Ian PhilippBiodemography of Aging Research Unit Social Science Research Institute, Duke University Durham North Carolina USA.
Yury LoikaBiodemography of Aging Research Unit Social Science Research Institute, Duke University Durham North Carolina USA.
Elena LoikoBiodemography of Aging Research Unit Social Science Research Institute, Duke University Durham North Carolina USA.
Irina CulminskayaBiodemography of Aging Research Unit Social Science Research Institute, Duke University Durham North Carolina USA.

Funding

Migrating the National Long Term Care Survey to the MedRIC Health and Aging Data EnclaveR01AG063971 · NIA · DUKE UNIVERSITY · PI STALLARD, P.J. ERIC · 2020 to 2024
$4.1M
ApoE2 and protective molecular signatures in Alzheimer's disease and agingR01AG061853 · NIA · DUKE UNIVERSITY · PI KULMINSKI, ALEXANDER M · 2018 to 2022
$3.9M
Personalized genetic profiles of risk and resilience in Alzheimer's and vascular diseasesR01AG065477 · NIA · DUKE UNIVERSITY · PI KULMINSKI, ALEXANDER M · 2020 to 2024
$3.8M
Dissecting genetic and non-genetic heterogeneity in predisposition to Alzheimer's disease and vascular traits in pleiotropic contextR01AG070488 · NIA · DUKE UNIVERSITY · PI KULMINSKI, ALEXANDER M, OUKRAINTSEVA, SVETLANA V. · 2020 to 2024
$2.8M
Molecular signatures of health and life span disparities between whites and African-Americans in the APOE regionR01AG047310 · NIA · DUKE UNIVERSITY · PI KULMINSKI, ALEXANDER M · 2015 to 2019
$2.5M
NIA NIH HHS R01 AG047310NIA NIH HHS R01 AG061853NIA NIH HHS R01 AG063971NIA NIH HHS R01 AG065477NIA NIH HHS R01 AG070488
6 · The paper itself

Abstract

introductionThe variability in apolipoprotein E (

methodsWe examined associations of compound genotypes (CompGs) comprising the

resultsThe absence and presence of the rs2075650 and/or rs12721046 minor alleles in the DISCUSSION: The Highlights: Younger White women carrying the lower-risk (LR) CompG are at small risk of AD.Black carriers of the LR CompG are at negligible risk of AD at 85 years and older.The higher-risk (HR) CompGs confer high AD risk in Whites and Blacks at 70 to 85 years.AD risk decreases with age for Hispanic/Lation women carrying the HR CompGs.Hispanic/Lation carriers of the LR CompG but not HR CompGs have higher AD risk than Blacks.

Indexed as

Alzheimer's disease riskAPOE gene clusterAPOE polymorphismhaplotypesrace/ethnic disparitiessex disparities in Alzheimer's disease

Identifiers

PMID38912305
PMCPMC11193136

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.