ArticleFrontiers in public health2024
The exposure to volatile organic compounds associate positively with overactive bladder risk in U.S. adults: a cross-sectional study of 2007-2020 NHANES.
Article in Frontiers in public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Article
- Association between cardiometabolic index and overactive bladder in adults: Evidence from the National Health and Nutrition Examination Survey 2011-2018.Asian journal of urology · 2026Article
- Association of weight-adjusted waist index (WWI) with overactive bladder (OAB): a cross-sectional study from NHANES 2005-2018.Scientific reports · 2025Article
- The association between magnesium depletion score (MDS) and overactive bladder (OAB) among the U.S. population.Journal of health, population, and nutrition · 2025Article
- The associations between volatile organic compounds exposure and urine flow rate in US adults: NHANES 2011-2020.American journal of clinical and experimental urology · 2025Article
- The association between education level and overactive bladder: Evidence from a U.S. population-based study.Preventive medicine reports · 2024Article
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5 authors.
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Abstract
Objective: The aim of this study was to comprehensively investigate the potential relationship between blood volatile organic compounds (VOCs) and overactive bladder (OAB) risk. Methods: A total of 11,183 participants from the 2007-2020 National Health and Nutrition Examination Survey (NHANES) were included in this cross-sectional study. We used multivariate logistic regression models to investigate the relationship between nine blood VOCs and OAB risk. Restricted cubic spline (RCS) analysis was used to investigate the dose-response relationship between blood VOCs and OAB. In addition, the overall association of blood VOCs with OAB risk was assessed by weighted quantile sum (WQS) regression model. Finally, we conducted subgroup analyses to explore the findings in different high-risk populations. Results: After adjusting for potential confounders, logistic regression analysis revealed that blood 2,5-dimethylfuran (aOR = 2.940, 95% CI: 1.096-7.890, Conclusions: The results of this study indicate that high exposure to VOCs is independently and positively associated with OAB risk in U.S. adults, particularly 2,5-dimethylfuran, benzene, and furan. In addition, age, gender, hypertension and alcohol consumption may influence the association. Our study provided novel epidemiologic evidence to explore the potential role of environmental pollutants in OAB.
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