Evidence map›Paper›PMID 38912213›Full record

ArticleJournal of biomedical optics2024

Depolarization diagrams for circularly polarized light scattering for biological particle monitoring.

Nozomi Nishizawa, Asato Esumi, Yukito Ganko

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nozomi NishizawaKitasato University, School of Science, Department of Physics, Sagamihara, Japan.ORCID 0000-0002-7292-0282
Asato EsumiKitasato University, School of Science, Department of Physics, Sagamihara, Japan.
Yukito GankoKitasato University, School of Science, Department of Physics, Sagamihara, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significance: The depolarization of circularly polarized light (CPL) caused by scattering in turbid media reveals structural information about the dispersed particles, such as their size, density, and distribution, which is useful for investigating the state of biological tissue. However, the correlation between depolarization strength and tissue parameters is unclear. Aim: We aimed to examine the generalized correlations of depolarization strength with the particle size and wavelength, yielding depolarization diagrams. Approach: The correlation between depolarization intensity and size parameter was examined for single and multiple scattering using the Monte Carlo simulation method. Expanding the wavelength width allows us to obtain depolarization distribution diagrams as functions of wavelength and particle diameter for reflection and transparent geometries. Results: CPL suffers intensive depolarization in a single scattering against particles of various specific sizes for its wavelength, which becomes more noticeable in the multiple scattering regime. Conclusions: The depolarization diagrams with particle size and wavelength as independent variables were obtained, which are particularly helpful for investigating the feasibility of various particle-monitoring methods. Based on the obtained diagrams, several applications have been proposed, including blood cell monitoring, early embryogenesis, and antigen-antibody interactions.

Indexed as

LightMonte Carlo MethodParticle SizeScattering, RadiationComputer SimulationNephelometry and Turbidimetryblood cell monitoringcancer detectioncircularly polarized lightdepolarizationlight scattering

Identifiers

PMID38912213
PMCPMC11191632

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.