Evidence map›Paper›PMID 38912153›Full record

ArticleIranian journal of public health2024

A New Formula Based on Simple Blood Indices to Differentiate Beta Thalassemia Trait from Iron Deficiency Anemia.

Parviz Shahmirzalou, Morteza Seyyed Hamze, Hassan Ebrahimpour Sadagheyani

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Article in Iranian journal of public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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3 · Its place in the literature

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1 citing paper in PubMed.

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5 · Who and what money

Authors and funding

3 authors.

Parviz ShahmirzalouDepartment of Biostatistics, Khoy University of Medical Sciences, Khoy, Iran.
Morteza Seyyed HamzeUrmia Branch, Islamic Azad University, Urmia, Iran.
Hassan Ebrahimpour SadagheyaniDepartment of Health Information Technology, School of Para Medicine, Neyshabur University of Medical Sciences, Neyshabur, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Thalassemia is an inherited blood disorder with a defect in the sufficient production of a protein called hemoglobin. We aimed to investigate the simple blood indices of patients with Beta Thalassemia Trait (BTT) and Iron Deficiency Anemia (IDA) to propose a new formula using logistic regression for differentiate two characteristics from each other. Methods: Among the 702 records of the BTT Counseling Center (Khoy, Iran-2022), 292 cases (219 iron deficiency anemia (IDA) and 73 BTT) were eligible for the study. Blood indices such as RBC, HGB, HbA2 described and used to diagnose two types of participants. Blood indices had high multicollinearity that was modified. Logistic regression for blood indices fitted and goodness of fit indices with Area Under ROC curve (AUC) estimated. Results: The average age of the participants was 24.56 yr. The status of Multicollinearity between independent variables was modified. The HGB, MCV, HbA2, and HbA variables were used in the model and only HbA2 status was significant ( Conclusion: In studies related to the differentiation of the BTT from IDA, the presence of the HbA2 index in the model and prediction is very necessary.

Indexed as

Beta thalassemiaBlood indexDifferentiation formulaIron deficiency anemiaLogistic regression

Identifiers

PMID38912153
PMCPMC11188649

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