Evidence map›Paper›PMID 38911927›Full record

ReviewOpen life sciences2024

New advances in protein engineering for industrial applications: Key takeaways.

Giles Obinna Ndochinwa, Qing-Yan Wang, Nkwachukwu Oziamara Okoro, Oyetugo Chioma Amadi, Tochukwu Nwamaka Nwagu, Chukwudi Innocent Nnamchi, Anene Nwabu Moneke, Arome Solomon Odiba

Abstract readReview
In one paragraph

Review in Open life sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Giles Obinna NdochinwaDepartment of Microbiology, Faculty of Biological Science, University of Nigeria, Nsukka, 410001, Nigeria.
Qing-Yan WangState Key Laboratory of Biomass Enzyme Technology, Guangxi Academy of Sciences, Nanning, Nanning, 530007, China.
Nkwachukwu Oziamara OkoroDepartment of Pharmaceutical and medicinal chemistry, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, 410001, Nigeria.
Oyetugo Chioma AmadiDepartment of Microbiology, Faculty of Biological Science, University of Nigeria, Nsukka, 410001, Nigeria.
Tochukwu Nwamaka NwaguDepartment of Microbiology, Faculty of Biological Science, University of Nigeria, Nsukka, 410001, Nigeria.
Chukwudi Innocent NnamchiDepartment of Microbiology, Faculty of Biological Science, University of Nigeria, Nsukka, 410001, Nigeria.
Anene Nwabu MonekeDepartment of Microbiology, Faculty of Biological Science, University of Nigeria, Nsukka, 410001, Nigeria.
Arome Solomon OdibaDepartment of Genetics and Biotechnology, Faculty of Biological Sciences, University of Nigeria, Nsukka, 410001, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advancements in protein/enzyme engineering have enabled the production of a diverse array of high-value compounds in microbial systems with the potential for industrial applications. The goal of this review is to articulate some of the most recent protein engineering advances in bacteria, yeast, and other microbial systems to produce valuable substances. These high-value substances include α-farnesene, vitamin B12, fumaric acid, linalool, glucaric acid, carminic acid, mycosporine-like amino acids, patchoulol, orcinol glucoside, d-lactic acid, keratinase, α-glucanotransferases, β-glucosidase, seleno-methylselenocysteine, fatty acids, high-efficiency β-glucosidase enzymes, cellulase, β-carotene, physcion, and glucoamylase. Additionally, recent advances in enzyme engineering for enhancing thermostability will be discussed. These findings have the potential to revolutionize various industries, including biotechnology, food, pharmaceuticals, and biofuels.

Indexed as

algaebacteriaEscherichia colifungiindustrial biotechnologyprotein and enzyme engineeringSaccharomyces cerevisiaethermostabilityyeast

Identifiers

PMID38911927
PMCPMC11193397

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.