Evidence map›Paper›PMID 38911550›Full record

ArticleFrontiers in bioengineering and biotechnology2024

Expanding the genetic toolbox for the obligate human pathogen

Nina Lautenschläger, Katja Schmidt, Carolin Schiffer, Thomas F Wulff, Karin Hahnke, Knut Finstermeier, Moïse Mansour, Alexander K W Elsholz, Emmanuelle Charpentier

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nina LautenschlägerMax Planck Unit for the Science of Pathogens, Berlin, Germany.
Katja SchmidtMax Planck Unit for the Science of Pathogens, Berlin, Germany.
Carolin SchifferMax Planck Unit for the Science of Pathogens, Berlin, Germany.
Thomas F WulffMax Planck Unit for the Science of Pathogens, Berlin, Germany.
Karin HahnkeMax Planck Unit for the Science of Pathogens, Berlin, Germany.
Knut FinstermeierMax Planck Unit for the Science of Pathogens, Berlin, Germany.
Moïse MansourMax Planck Unit for the Science of Pathogens, Berlin, Germany.
Alexander K W ElsholzMax Planck Unit for the Science of Pathogens, Berlin, Germany.
Emmanuelle CharpentierMax Planck Unit for the Science of Pathogens, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic tools form the basis for the study of molecular mechanisms. Despite many recent advances in the field of genetic engineering in bacteria, genetic toolsets remain scarce for non-model organisms, such as the obligatory human pathogen

Indexed as

genetic engineeringinducible promoterplasmid collectionreporter genescarless gene deletionStreptococcus pyogenessynthetic biology

Identifiers

PMID38911550
PMCPMC11190166

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.