Evidence map›Paper›PMID 38911346›Full record

ArticleLancet regional health. Americas2024

Simulation-based economic evaluation of the Wolbachia method in Brazil: a cost-effective strategy for dengue control.

Ivan Ricardo Zimmermann, Ricardo Ribeiro Alves Fernandes, Márcia Gisele Santos da Costa, Márcia Pinto, Henry Maia Peixoto

Abstract read
In one paragraph

Article in Lancet regional health. Americas, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. The impact of large-scale release ofLancet regional health. Americas · 2026
    Article
  3. Review
  4. Article
  5. Long-Term Durability and Public Health Impact of City-WideTropical medicine and infectious disease · 2025
    Article
  6. ExploitingPathogens (Basel, Switzerland) · 2025
    Review
  7. Article
  8. Trends in dengue incidence and lethality: interrupted time series analysis, Brazil, 2001-2022.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2025
    Article
  9. Article
  10. Review
  11. Cost-effectiveness of aLancet regional health. Americas · 2024
    Article
  12. Article
  13. The greatest Dengue epidemic in Brazil: Surveillance, Prevention, and Control.Revista da Sociedade Brasileira de Medicina Tropical · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ivan Ricardo ZimmermannDepartment of Public Health, University of Brasilia, Brasilia, Brazil.
Ricardo Ribeiro Alves FernandesHealth Technology Assessment Unit, National Cancer Institute, Rio de Janeiro, Brazil.
Márcia Gisele Santos da CostaHealth Technology Assessment Unit, National Cardiology Institute, Rio de Janeiro, Brazil.
Márcia PintoFernandes Figueira Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.
Henry Maia PeixotoCenter for Tropical Medicine, University of Brasilia, Brasilia, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Dengue virus (DENV) is an arbovirus transmitted by Methods: We estimated the economic impact of implementing the Findings: Without Wolbachia, the model projected 1,762,688 reported dengue cases over 20 years. Implementing the Wolbachia method would avert at least 1,295,566 dengue cases, resulting in lower costs and greater effectiveness in all simulated cities. On average, for every 1000 inhabitants followed for 20 years, the Wolbachia method yielded a cost difference of USD 538,233.68 (BRL 2,691,168.40) and averted 5.56 DALYs. Net monetary benefits (NMB) were positive in all seven cities, ranging from USD 110.72 (BRL 553.59) to USD 1399.19 (BRL 6995.95) per inhabitant. Alternative scenarios have also shown a favourable return on investment with a positive benefit-cost ratio (BCR). Interpretation: Wolbachia is likely a cost-effective strategy in the Brazilian context, consistent with international studies. Sensitivity analysis and alternative scenarios confirmed the robustness of the results. Funding: This study was funded by the Wellcome Trust under a grant (224459/Z/21/Z).

Indexed as

BrazilCost-effectivenessDengueWolbachia

Identifiers

PMID38911346
PMCPMC11190723

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.