Evidence map›Paper›PMID 38910785›Full record

ArticleCureus2024

Rapid Corneal Calcification Following Endothelial Keratoplasty: A Case Report.

Atsuhiko Fukuto, Koichiro Shinji, Suzu Deie, Tai-Ichiro Chikama

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Atsuhiko FukutoDepartment of Ophthalmology and Visual Sciences, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, JPN.
Koichiro ShinjiDepartment of Ophthalmology and Visual Sciences, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, JPN.
Suzu DeieDepartment of Ophthalmology and Visual Sciences, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, JPN.
Tai-Ichiro ChikamaDepartment of Ophthalmology and Visual Sciences, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Corneal calcification typically progresses slowly but can occasionally advance rapidly. This report details severe stromal calcification following repeat Descemet's stripping automated endothelial keratoplasty (DSAEK) in a 75-year-old patient with diabetes, hypertension, and prior ocular surgeries, including cataract surgery, intraocular lens extraction with suturing, and trabeculectomy. Persistent epithelial defects after the surgery led to rapid central stromal calcification within four weeks, significantly reducing visual acuity. Management included switching from betamethasone sodium phosphate to fluorometholone, facilitating complete epithelial recovery within two months. However, persistent stromal opacity necessitated a subsequent penetrating keratoplasty. Infrared absorption spectrophotometry identified calcium phosphate as the primary component of the calcification. This case highlights the importance of vigilant monitoring and proactive management of epithelial defects to prevent rapid calcification following endothelial keratoplasty.

Indexed as

calcium phosphatecorneal calcificationcorneal opacitydsaekpersistent epithelial defect

Identifiers

PMID38910785
PMCPMC11193668

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.