Evidence map›Paper›PMID 38910521›Full record

ArticleBiomaterials science2024

Hypothermic and cryogenic preservation of cardiac tissue-engineered constructs.

Jasmijn Janssen, Nino Chirico, Madison J Ainsworth, Gerardo Cedillo-Servin, Martina Viola, Inge Dokter, Tina Vermonden, Pieter A Doevendans, Margarida Serra, Ilja K Voets and 6 more

Abstract read
In one paragraph

Article in Biomaterials science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Jasmijn JanssenDepartment of Cardiology, Experimental Cardiology Laboratory, Circulatory Health Research Center, Regenerative Medicine Center Utrecht, University Utrecht, University Medical Center Utrecht, Uppsalalaan 8, Utrecht, 3584 CT, The Netherlands. A.vanMil@umcutrecht.nl.
Nino ChiricoDepartment of Cardiology, Experimental Cardiology Laboratory, Circulatory Health Research Center, Regenerative Medicine Center Utrecht, University Utrecht, University Medical Center Utrecht, Uppsalalaan 8, Utrecht, 3584 CT, The Netherlands. A.vanMil@umcutrecht.nl.
Madison J AinsworthDepartment of Orthopedics, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, 3584 CX, The Netherlands.ORCID http://orcid.org/0000-0002-7768-6392
Gerardo Cedillo-ServinDepartment of Orthopedics, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, 3584 CX, The Netherlands.
Martina ViolaDepartment of Orthopedics, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, 3584 CX, The Netherlands.
Inge DokterDepartment of Cardiology, Experimental Cardiology Laboratory, Circulatory Health Research Center, Regenerative Medicine Center Utrecht, University Utrecht, University Medical Center Utrecht, Uppsalalaan 8, Utrecht, 3584 CT, The Netherlands. A.vanMil@umcutrecht.nl.
Tina VermondenDepartment of Pharmaceutical Sciences, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Universiteitsweg 99, 3508 TB Utrecht, The Netherlands.ORCID http://orcid.org/0000-0002-6047-5900
Pieter A DoevendansNetherlands Heart Institute (NLHI), Utrecht, 3511 EP, The Netherlands.
Margarida SerraiBET, Instituto de Biologia Experimental e Tecnológica, Oeiras, Portugal.
Ilja K VoetsLaboratory of Self-Organizing Soft Matter, Department of Chemical Engineering and Chemistry & Institute of Complex Molecular Systems, Eindhoven University of Technology, Eindhoven 5600 MB, PO box 513, The Netherlands.ORCID http://orcid.org/0000-0003-3543-4821
Jos MaldaDepartment of Orthopedics, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, 3584 CX, The Netherlands.ORCID http://orcid.org/0000-0002-9241-7676
Miguel CastilhoDepartment of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, 5612 AE, The Netherlands.ORCID http://orcid.org/0000-0002-4269-5889
Linda W van LaakeDepartment of Cardiology, Experimental Cardiology Laboratory, Circulatory Health Research Center, Regenerative Medicine Center Utrecht, University Utrecht, University Medical Center Utrecht, Uppsalalaan 8, Utrecht, 3584 CT, The Netherlands. A.vanMil@umcutrecht.nl.
Joost P G SluijterDepartment of Cardiology, Experimental Cardiology Laboratory, Circulatory Health Research Center, Regenerative Medicine Center Utrecht, University Utrecht, University Medical Center Utrecht, Uppsalalaan 8, Utrecht, 3584 CT, The Netherlands. A.vanMil@umcutrecht.nl.
Vasco Sampaio-PintoDepartment of Cardiology, Experimental Cardiology Laboratory, Circulatory Health Research Center, Regenerative Medicine Center Utrecht, University Utrecht, University Medical Center Utrecht, Uppsalalaan 8, Utrecht, 3584 CT, The Netherlands. A.vanMil@umcutrecht.nl.
Alain van MilDepartment of Cardiology, Experimental Cardiology Laboratory, Circulatory Health Research Center, Regenerative Medicine Center Utrecht, University Utrecht, University Medical Center Utrecht, Uppsalalaan 8, Utrecht, 3584 CT, The Netherlands. A.vanMil@umcutrecht.nl.ORCID http://orcid.org/0000-0001-9906-5047

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac tissue engineering (cTE) has already advanced towards the first clinical trials, investigating safety and feasibility of cTE construct transplantation in failing hearts. However, the lack of well-established preservation methods poses a hindrance to further scalability, commercialization, and transportation, thereby reducing their clinical implementation. In this study, hypothermic preservation (4 °C) and two methods for cryopreservation (

Indexed as

CryopreservationMyocytes, CardiacTissue EngineeringCells, CulturedCell SurvivalHumansHydrogelsInduced Pluripotent Stem CellsTissue ScaffoldsHydrogels

Identifiers

PMID38910521
PMCPMC11265564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.