Evidence map›Paper›PMID 38910495›Full record

ArticleJournal of Zhejiang University. Science. B2024

Hemodialysis bilayer bionic blood vessels developed by the mechanical stimulation of hepatitis B viral X(

Hongyi Liu, Yuanyuan Zhou, Peng Guo, Xiongwei Zheng, Weibin Chen, Shichao Zhang, Yu Fu, Xu Zhou, Zheng Wan, Bin Zhao and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Zhejiang University. Science. B, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hongyi LiuDepartment of Oncology and Vascular Interventional Radiology, Zhongshan Hospital Affiliated to Xiamen University, School of Medicine, Xiamen University, Xiamen 361004, China.
Yuanyuan ZhouDepartment of Oncology and Vascular Interventional Radiology, Zhongshan Hospital Affiliated to Xiamen University, School of Medicine, Xiamen University, Xiamen 361004, China. 15959223830@163.com.
Peng GuoDepartment of Oncology and Vascular Interventional Radiology, Zhongshan Hospital Affiliated to Xiamen University, School of Medicine, Xiamen University, Xiamen 361004, China.
Xiongwei ZhengSchool of Medicine, Xiamen University, Xiamen 361102, China.
Weibin ChenDepartment of Oncology and Vascular Interventional Radiology, Zhongshan Hospital Affiliated to Xiamen University, School of Medicine, Xiamen University, Xiamen 361004, China.
Shichao ZhangSchool of Medicine, Xiamen University, Xiamen 361102, China.
Yu FuDepartment of Oncology and Vascular Interventional Radiology, Zhongshan Hospital Affiliated to Xiamen University, School of Medicine, Xiamen University, Xiamen 361004, China.
Xu ZhouDepartment of Oncology and Vascular Interventional Radiology, Zhongshan Hospital Affiliated to Xiamen University, School of Medicine, Xiamen University, Xiamen 361004, China.
Zheng WanDepartment of Oncology and Vascular Interventional Radiology, Zhongshan Hospital Affiliated to Xiamen University, School of Medicine, Xiamen University, Xiamen 361004, China.
Bin ZhaoXiamen Health and Medical Big Data Center, Xiamen 361008, China.
Yilin ZhaoDepartment of Oncology and Vascular Interventional Radiology, Zhongshan Hospital Affiliated to Xiamen University, School of Medicine, Xiamen University, Xiamen 361004, China. zyllbz@gmail.com.

Funding

the National Natural Science Foundation of China 81770294the Natural Science Foundation of Fujian Province 2023J05261
6 · The paper itself

Abstract

Artificial vascular graft (AVG) fistula is widely used for hemodialysis treatment in patients with renal failure. However, it has poor elasticity and compliance, leading to stenosis and thrombosis. The ideal artificial blood vessel for dialysis should replicate the structure and components of a real artery, which is primarily maintained by collagen in the extracellular matrix (ECM) of arterial cells. Studies have revealed that in hepatitis B virus (HBV)-induced liver fibrosis, hepatic stellate cells (HSCs) become hyperactive and produce excessive ECM fibers. Furthermore, mechanical stimulation can encourage ECM secretion and remodeling of a fiber structure. Based on the above factors, we transfected HSCs with the hepatitis B viral X (

Indexed as

Hepatic Stellate CellsRenal DialysisAnimalsBionicsBlood Vessel ProsthesisCollagenExtracellular MatrixHepatitis B virusHumansPolyestersPolyurethanesRabbitsTissue EngineeringTissue ScaffoldsTrans-ActivatorsTransfectionCollagenhepatitis B virus X proteinpolycaprolactonePolyestersPolyurethanesTrans-ActivatorsViral Regulatory and Accessory ProteinsComposite bilayer bionic blood vesselExtracellular matrix (ECM)Hepatic stellate cells (HSCs)Hepatitis B viral X (HBX) geneMechanical force

Identifiers

PMID38910495
PMCPMC11199092

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.