ArticleScientific reports2024
Prevalence of peripheral neuropathy, amputation, and quality of life in patients with diabetes mellitus.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Measurement Properties of Instruments Used to Assess Diabetic Foot: An Umbrella Review.Journal of diabetes research · 2026Pooled it
- Experiences and needs of individuals living with diabetic peripheral neuropathy: a qualitative systematic review and meta-synthesis.Frontiers in neurologyPooled it
- The effects of high-intensity interval training on glucose metabolism, inflammatory responses, and functional recovery in patients with diabetic peripheral neuropathy.Frontiers in endocrinology · 2026Trial
- Clinical Profile of Documented Diabetic Peripheral Neuropathy by GLP-1-Based Medication Status: A Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2026Article
- Incidence and Risk Factors of Stump Complications Following Amputation in Patients With Diabetes: A Retrospective Analysis of the Nationwide Inpatient Sample.World journal of surgery · 2026Article
- Redox-Driven Blood-Nerve Barrier Dysfunction in Diabetic Peripheral Neuropathy: Mechanisms and Therapeutic Opportunities.Antioxidants (Basel, Switzerland) · 2026Review
- Noninvasive MRI biomarkers in diabetic neuropathy: correlation with electrophysiology, clinical scores, and nerve pathology.Neuroradiology · 2026Review
- Screening practices and risk factors for diabetic foot complications among patients with diabetes at a tertiary centre in Riyadh, Saudi Arabia.Journal of family medicine and primary care · 2026Article
- Diabetic Peripheral Neuropathy: New Diagnostics and Treatment Perspectives.Drugs & aging · 2026Review
- Endocrinologists' Perspectives on Early Screening for Diabetic Peripheral Neuropathy: A Phenomenological Study in Four Chinese Based Hospitals.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Mechanistic Insights into the Wound Healing Activity of Plant Species in Diabetic Ulcers.Current issues in molecular biology · 2025Review
- Assessment of biomarkers associated with renal decline for prediction of incident distal sensory polyneuropathy in type 2 diabetes.Scientific reports · 2025Article
- Diabetes mellitus in Pakistan: prevalence and preventive management strategies - a comprehensive literature review.Cardiovascular diabetology. Endocrinology reports · 2025Review
- Article
- Targeted neural stem cell-derived extracellular vesicles loaded with Sinomenine alleviate diabetic peripheral neuropathy via WNT5a/TRPV1 pathway modulation.Journal of nanobiotechnology · 2025Article
- Health-related quality of life related to diabetes multisensory deficits and derealization.Scientific reports · 2025Article
- Clinical Phenotypes of Diabetic Peripheral Neuropathy: Implications for Phenotypic-Based Therapeutics Strategies.Diabetes & metabolism journal · 2025Review
- Diabetic wound healing via a co-delivery system for bone marrow derived stem cells and euphorbia hirta extract: an in vitro and in vivo study.Journal of materials science. Materials in medicine · 2025Article
- Article
- Frailty Prediction Model for Elderly Diabetic Peripheral Neuropathy Patients.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
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Authors and funding
9 authors.
Funding
Abstract
Peripheral neuropathy and amputation are common complications of diabetes mellitus (DM) that significantly impact the quality of life of the affected individuals. This study aims to investigate the prevalence of peripheral neuropathy, the level of amputation, and the quality of life in patients with DM. This cross-sectional study was conducted after approval of the synopsis involving 225 diagnosed patients with DM on pre-defined eligibility criteria, selected from public sector OPDs, specialized diabetes centres, and centres manufacturing orthotics and prosthetics. Data were collected through interviews, observations, and the administration of the Michigan Neuropathy Screening Instrument and the Asian Diabetes Quality of Life Questionnaire. The level of amputation was recorded for each participant. Data was entered into SPSS, and results were synthesized. Pearson correlation is applied to find an association between gender and the quality of life of the participants, while P ≤ 0.05 will be considered significant. The prevalence of peripheral neuropathy in a sample of 225, based on a self-administered questionnaire, was (44.4%), and in terms of foot examination was (51.1%). As people progressed in age, the prevalence increased to 20.0% in patients above 60 years and 8.9% in ≤ 35 years of age. The majority of participants (56.0%) have had DM for less than five years. Females were 57.8% of the study population, while 97.8% of participants had type II DM. Below-knee amputation of the right limb was observed in 22(9.8%) of the participants. The QoL was poor in the majority of the participants (96.9%) patients with DM (P = 0.638 and T = -0.471). This cross-sectional study highlights a high prevalence of peripheral neuropathy and amputation and poor QoL in patients with diabetic mellitus.
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