Evidence map›Paper›PMID 38909159›Full record

SynthesisPediatric research2025

Cardiac evaluation of patients with juvenile dermatomyositis.

Gökmen Akgün, Betül Sözeri, Eviç Zeynep Başar, Nihal Şahin, Yunus Emre Bayrak, Kadir Ulu, Hüseyin Salih Güngör, Mustafa Doğan, Taliha Öner, Mehmet Karacan and 3 more

Abstract readSystematic Review
In one paragraph

Synthesis in Pediatric research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Gökmen AkgünDepartment of Pediatric Cardiology, City Hospital, Kocaeli, Turkey.
Betül SözeriDepartment of Pediatric Rheumatology, University of Health Sciences, Ümraniye Research and Training Hospital, Istanbul, Turkey.
Eviç Zeynep BaşarDepartment of Pediatric Cardiology, Kocaeli University, Faculty of Medicine, Kocaeli, Turkey.
Nihal ŞahinDepartment of Pediatric Rheumatology, Kocaeli University, Faculty of Medicine, Kocaeli, Turkey.
Yunus Emre BayrakDepartment of Pediatric Rheumatology, Kocaeli University, Faculty of Medicine, Kocaeli, Turkey.
Kadir UluDepartment of Pediatric Rheumatology, University of Health Sciences, Ümraniye Research and Training Hospital, Istanbul, Turkey.
Hüseyin Salih GüngörDepartment of Pediatric Cardiology, Kocaeli University, Faculty of Medicine, Kocaeli, Turkey.
Mustafa DoğanDepartment of Pediatric Cardiology, Kocaeli University, Faculty of Medicine, Kocaeli, Turkey.
Taliha ÖnerDepartment of Pediatric Cardiology, University of Health Sciences, Ümraniye Research and Training Hospital, Istanbul, Turkey.
Mehmet KaracanDepartment of Pediatric Cardiology, University of Health Sciences, Ümraniye Research and Training Hospital, Istanbul, Turkey.
Kadir BabaoğluDepartment of Pediatric Cardiology, Kocaeli University, Faculty of Medicine, Kocaeli, Turkey.
Yonca AnıkDepartment of Radiology, Kocaeli University, Faculty of Medicine, Kocaeli, Turkey.
Hafize Emine SönmezDepartment of Pediatric Rheumatology, Kocaeli University, Faculty of Medicine, Kocaeli, Turkey. eminesonmez@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present study aims to evaluate possible cardiac involvement in juvenile dermatomyositis (JDM) patients by conventional methods and cardiac magnetic resonance imaging (MRI) along with a systematic review of the literature on cardiac features in JDM.

methodsThe study group consisted of JDM patients who underwent cardiac MRI. We conducted a systematic review of the published literature involving JDM patients with cardiac involvement.

resultsIn the present study, although baseline cardiologic evaluations including electrocardiography and echocardiography were within normal limits, we showed late gadolinium enhancement on cardiac MRI in 3 of 11 JDM patients. In the literature review, we identified 25 articles related to cardiac involvement in JDM. However, none of them, except one case report, included cardiac MRI of JDM patients.

conclusionCardiac abnormalities have been reported among the less frequent findings in patients with JDM. Cardiovascular complications during the long-term disease course are a leading cause of morbidity and mortality in these patients. Early detection of cardiac involvement by cardiac MRI in patients with JDM and aggressive treatment of them may improve the clinical course of these patients. IMPACT: The myocardium in patients with JDM may be involved by inflammation. Myocardial involvement may be evaluated by using contrast-enhanced cardiac MRI. This is the first study evaluating cardiac involvement by cardiac MRI in JDM patients. MRI may show early cardiac involvement in patients whose baseline cardiologic evaluations are within normal limits. Early detection of cardiac involvement by cardiac MRI may improve the long-term prognosis of patients with JDM.

Indexed as

DermatomyositisHeartChildContrast MediaEchocardiographyElectrocardiographyHumansMagnetic Resonance ImagingMyocardiumContrast Media

Identifiers

PMID38909159
PMCPMC11798830

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.