Evidence map›Paper›PMID 38909072›Full record

ArticleNPJ microgravity2024

Weightlessness leads to an increase granulosa cells in the growing follicle.

Anna Yu Kikina, Mariia S Matrosova, Elena Yu Gorbacheva, Ksenia K Gogichaeva, Konstantin A Toniyan, Valery V Boyarintsev, Oleg V Kotov, Irina V Ogneva

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NPJ microgravity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anna Yu KikinaGagarin Research and Test Cosmonaut Training Center, 141160, Star City, Moscow Region, Russia.
Mariia S MatrosovaRadiology Department, European Medical Center, 129090, Moscow, Russia.
Elena Yu GorbachevaCell Biophysics Lab, State Scientific Center of the Russian Federation Institute of Biomedical Problems of the Russian Academy of Sciences, 123007, Moscow, Russia.
Ksenia K GogichaevaCell Biophysics Lab, State Scientific Center of the Russian Federation Institute of Biomedical Problems of the Russian Academy of Sciences, 123007, Moscow, Russia.
Konstantin A ToniyanCell Biophysics Lab, State Scientific Center of the Russian Federation Institute of Biomedical Problems of the Russian Academy of Sciences, 123007, Moscow, Russia.
Valery V BoyarintsevEmergency and Extreme Medicine Department, Central State Medical Academy UDP RF, 121359, Moscow, Russia.
Oleg V KotovCell Biophysics Lab, State Scientific Center of the Russian Federation Institute of Biomedical Problems of the Russian Academy of Sciences, 123007, Moscow, Russia.
Irina V OgnevaCell Biophysics Lab, State Scientific Center of the Russian Federation Institute of Biomedical Problems of the Russian Academy of Sciences, 123007, Moscow, Russia. iogneva@yandex.ru.ORCID http://orcid.org/0000-0003-0125-5876

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The participation of women in space programs of increasing flight duration requires research of their reproductive system from the perspective of subsequent childbearing and healthy aging. For the first time, we present hormonal and structural data on the dynamics of recovery after a 157-day space flight in a woman of reproductive age. There were no clinically significant changes in the reproductive system, but detailed analysis shows that weightlessness leads to an increase in the proportion of early antral follicles and granulosa cells in large antral follicles. Returning to Earth's gravity reduces the number and diameter of early antral follicles.

Identifiers

PMID38909072
PMCPMC11193763

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.