Evidence map›Paper›PMID 38908841›Full record

ArticleBMJ open2024

Addressing the unmet needs of women with breast cancer in Mexico: a non-randomised pilot study of the digital ePRO intervention.

Saúl Eduardo Contreras Sánchez, Svetlana V Doubova, Ingrid Patricia Martinez Vega, Rocío Grajales Álvarez, Ricardo Villalobos Valencia, Abdel Karim Dip Borunda, Lorena Lio Mondragón, Wendy Jazmín Martínez Pineda, Jose Gustavo Nuñez Cerrillo, Alma Diana Huerta López and 12 more

2 registry-linked trialsAbstract read
In one paragraph

Article in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05925257 phase2unknown statusnot on this map

Design and Evaluation of the Effectiveness of a Digital Health Intervention to Improve Health Care and Outcomes for Cancer Patients

TypeinterventionalSponsorCoordinación de Investigación en Salud, MexicoRan2024 to 2025Enrolled410ConditionsBreast CancerArmsePRO application and proactive clinical care with nurses.
NCT07668440 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Preliminary Assessment of the Effects, Usability, Satisfaction, Barriers, and Benefits of a Remote, Multidomain Intervention Supported by a Website to Prevent Cognitive Decline in Older Adults

TypeinterventionalSponsorInstituto Mexicano del Seguro SocialRan2026 to 2027Enrolled71ConditionsCoginitive DysfunctionArmsMulti-domain intervention: Physical activity, cognitive training, and educational program through a website
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Models, outcomes, barriers, and facilitators of supportive care in cancer: a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Saúl Eduardo Contreras SánchezEpidemiology and Health Services Research Unit CMN Siglo XXI, Mexican Institute of Social Security, Mexico City, Mexico.
Svetlana V DoubovaEpidemiology and Health Services Research Unit CMN Siglo XXI, Mexican Institute of Social Security, Mexico City, Mexico svetlana.doubova@gmail.com.ORCID 0000-0002-0521-7095
Ingrid Patricia Martinez VegaEpidemiology and Health Services Research Unit CMN Siglo XXI, Mexican Institute of Social Security, Mexico City, Mexico.
Rocío Grajales ÁlvarezDepartment of Oncology, Oncology Hospital CMN Siglo XXI, Mexican Institute of Social Security, Mexico City, Mexico.
Ricardo Villalobos ValenciaDepartment of Oncology, Oncology Hospital CMN Siglo XXI, Mexican Institute of Social Security, Mexico City, Mexico.
Abdel Karim Dip BorundaDepartment of Oncology, Oncology Hospital CMN Siglo XXI, Mexican Institute of Social Security, Mexico City, Mexico.
Lorena Lio MondragónDepartment of Radiation Oncology, Oncology Hospital CMN Siglo XXI, Mexican Institute of Social Security, Mexico City, Mexico.
Wendy Jazmín Martínez PinedaDepartment of Radiation Oncology, Oncology Hospital CMN Siglo XXI, Mexican Institute of Social Security, Mexico City, Mexico.
Jose Gustavo Nuñez CerrilloDepartment of Oncology, Speciality Hospital CMN Manuel Ávila Camacho, Mexican Institute of Social Security, Mexico City, Mexico.
Alma Diana Huerta LópezDepartment of Oncology, Speciality Hospital CMN Manuel Ávila Camacho, Mexican Institute of Social Security, Mexico City, Mexico.
Rita Zalapa VelázquezDepartment of Oncology, Speciality Hospital CMN Manuel Ávila Camacho, Mexican Institute of Social Security, Mexico City, Mexico.
Valeria Mendoza OrtizDepartment of Oncology, Speciality Hospital CMN Manuel Ávila Camacho, Mexican Institute of Social Security, Mexico City, Mexico.
Víctor Javier Vázquez ZamoraDepartment of Oncology, Speciality Hospital CMN Manuel Ávila Camacho, Mexican Institute of Social Security, Mexico City, Mexico.
Álvaro José Montiel JarquínDepartment of Education and Research, Speciality Hospital CMN Manuel Ávila Camacho, Mexican Institute of Social Security, Mexico City, Mexico.
Arturo García GaliciaDepartment of Education and Research, Speciality Hospital CMN Manuel Ávila Camacho, Mexican Institute of Social Security, Mexico City, Mexico.
Enrique Isay Talamantes GómezDepartment of Oncology, Obstetrics and Gynecology Hospital CMN La Raza, Mexican Institute of Social Security, Mexico City, Mexico.
Roberto Sánchez ReyesDepartment of Oncology, Obstetrics and Gynecology Hospital CMN La Raza, Mexican Institute of Social Security, Mexico City, Mexico.
Jaqueline Aguirre GómezDepartment of Oncology, Obstetrics and Gynecology Hospital CMN La Raza, Mexican Institute of Social Security, Mexico City, Mexico.
María Eugenia Ayala AnzuresDepartment of Oncology, Obstetrics and Gynecology Hospital CMN La Raza, Mexican Institute of Social Security, Mexico City, Mexico.
Marta Zapata TarrésResearch Coordination, IMSS Foundation, Mexican Institute of Social Security, Mexico City, Mexico.
Adriana MonroyDepartment of Oncology, Hospital General de México Dr Eduardo Liceaga, Mexico City, Mexico.
Hannah H LeslieDivision of Prevention Science, University of California, San Francisco, San Francisco, California, USA.ORCID 0000-0002-7464-3645

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to explore the acceptability, feasibility, usability, and preliminary effect of an electronic patient-reported outcome (ePRO) intervention for patients with breast cancer in Mexico.

designWe conducted a multimethod non-randomised pilot study. We used a pre-test/post-test design for quantitative assessment of the intervention's effect on patients' supportive care needs and quality of life. We conducted in-depth interviews (IDIs) with participants and healthcare workers to explore the intervention's benefits and barriers and understand its feasibility.

participants50 women aged 20-75 diagnosed with stage I-III breast cancer were enrolled within 2 weeks of starting neoadjuvant or adjuvant treatment with chemotherapy or radiotherapy. We excluded illiterate women and those with visual impairment, cognitive disability or severe depression. IDIs were conducted with 18 participants and 10 healthcare providers.

settingOncology services in three public hospitals of the Mexican Social Security Institute.

interventionThe ePRO intervention consisted of a responsive web application for weekly symptom reporting combined with proactive follow-up by nurses guided by predefined clinical algorithms for 6 weeks.

results50 women were enrolled out of 66 eligible patients approached (75.8%). All 50 completed the 4-week follow-up assessment (100% retention). Completion of the symptom registry declined from 100% in week 1 to 66% in week 6. Participants experienced decreases in supportive care needs and increased quality of life. The ePRO application was rated highly usable. Participants and health professionals both perceived intervention benefits. Drawbacks included poor fit for women receiving radiotherapy and challenges using the application for women with low digital literacy or experiencing severe symptoms.

conclusionsThis pilot study provided evidence of the high usability and potential efficacy of a web-based ePRO intervention. We revised recruitment during the pilot to include multiple facilities, and we will further revise for the randomised trial to address barriers to successful ePRO implementation. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov ID: NCT05925257.

Indexed as

Breast NeoplasmsPatient Reported Outcome MeasuresQuality of LifeAdultAgedFeasibility StudiesFemaleHumansInternet-Based InterventionMexicoMiddle AgedPilot ProjectsYoung Adultbreast tumoursehealthnurses

Identifiers

PMID38908841
PMCPMC11328655

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.