Evidence map›Paper›PMID 38908422›Full record

ArticleAmerican heart journal2024

Incident stroke in individuals with peripartum cardiomyopathy.

Chinwe Ibeh, Erin R Kulick, Amelia K Boehme, Alexander M Friedman, Eliza C Miller, Natalie A Bello

Abstract read
In one paragraph

Article in American heart journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chinwe IbehDivision of Stroke, Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY.
Erin R KulickDepartment of Epidemiology and Biostatistics, College of Public Health, Temple University, Philadelphia, PA.
Amelia K BoehmeDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY.
Alexander M FriedmanDepartment of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, New York, NY.
Eliza C MillerDivision of Stroke, Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY.
Natalie A BelloDepartment of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA. Electronic address: NatalieAnn.Bello@cshs.org.

Funding

Research Education CoreP30AG059303 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Jennifer Jaie Manly · 2018 to 2026
$6.0M
Modeling informatics data to track maternal risk and care qualityR01HD104943 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Alexander M Friedman, Sarah Collins Rossetti · 2022 to 2026
$3.4M
Stroke Trials Network of Columbia and CornellU24NS107237 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI EDWARD SANDER CONNOLLY, Randolph S Marshall · 2018 to 2026
$3.1M
Cardiac Manifestations of PreeclampsiaR01HL153382 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BELLO, NATALIE A · 2020 to 2023
$1.6M
Neurovascular Unit Dysfunction in Women with Severe PreeclampsiaK23NS107645 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MILLER, ELIZA C · 2019 to 2023
$1.1M
EnCoRe MOMS: Engaging Communities to Reduce Morbidity from Maternal SepsisUG3HD111247 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FRIEDMAN, ALEXANDER M, GOFFMAN, DENA · 2022 to 2022
$958k
Blood Pressure Measurement and Hypertension in PregnancyK23HL136853 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BELLO, NATALIE A · 2018 to 2022
$948k
NHLBI NIH HHS K23 HL136853NHLBI NIH HHS R01 HL153382NIA NIH HHS P30 AG059303NICHD NIH HHS R01 HD104943NICHD NIH HHS UG3 HD111247NINDS NIH HHS K23 NS107645NINDS NIH HHS L30 NS103295NINDS NIH HHS U24 NS107237
6 · The paper itself

Abstract

backgroundPeripartum cardiomyopathy (PPCM), a form of heart failure with reduced ejection fraction (HFrEF) that occurs during the final month of pregnancy through the first 5 months postpartum, is associated with heightened risk for maternal morbidity and mortality. Stroke is a common complication of HFrEF but there is limited data on the incidence of stroke in PPCM.

methodsUsing statewide, nonfederal administrative data from 2000 to 2015, we analyzed age-adjusted risk of stroke within 3 years after PPCM-associated pregnancies.

resultsPPCM was associated with a greater than 4-fold increased risk of pregnancy-related stroke (aHR 4.7, 95% CI: 3.0-7.5). This risk was highest at the time of PPCM diagnosis but remained elevated in the first postpartum year.

conclusionOur findings confirm the strong association between PPCM and stroke, with risk that persists throughout and after the peripartum period.

Indexed as

CardiomyopathiesPeripartum PeriodPregnancy Complications, CardiovascularStrokeAdultFemaleHeart FailureHumansIncidencePregnancyPuerperal DisordersRetrospective StudiesRisk FactorsStroke Volume

Identifiers

PMID38908422
PMCPMC11330711

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.