Evidence map›Paper›PMID 38907831›Full record

SynthesisQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2024

Effect of breathing exercises on patients with interstitial lung disease: A systematic review and meta-analysis.

Jia Fan, Yuyang Chang, Siming Cheng, Bing Liang, Danhua Qu

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jia Fan *Department of Respiratory and Critical Care Medicine, The Second Hospital of Jilin University, Changchun, 130022, Jilin, China.
Yuyang Chang *Department of Cardiovascular Medicine, The Second Hospital of Jilin University, Changchun, 130022, Jilin, China.
Siming ChengJilin General Aviation Vocational and Technical College, Jilin, 037304, Jilin, China.
Bing LiangSchool of Nursing, Jilin University, Changchun, 130021, Jilin, China. liangbing716@jlu.edu.cn.ORCID http://orcid.org/0000-0002-0048-9307
Danhua QuDepartment of Respiratory and Critical Care Medicine, The Second Hospital of Jilin University, Changchun, 130022, Jilin, China. qudh@jlu.edu.cn.ORCID http://orcid.org/0009-0001-2705-1567

Funding

Jilin Province Health Science and Technology Capability Improvement Project 2021JC041Jilin Province Health Special Project Discipline Talent Development Project 2020SCZT055
6 · The paper itself

Abstract

purposeThis study was designed to synthesize the efficacy and safety of breathing exercises in interstitial lung disease (ILD) patients by reviewing the literature and comparing the impact of different control group types, ILD subtypes, breathing exercise action modes or methods, and intervention durations on clinical efficacy.

methodsSystematic searches were conducted across 9 electronic databases, including PubMed, to retrieve English and Chinese studies reporting on ILD patients from inception to February 12, 2024. Study selection and data extraction were independently conducted by two researchers. The quality of the included studies was assessed using the Cochrane risk of bias tool. The data were analysed using RevMan 5.4 and STATA 17.0 software.

resultsThe search identified 25 studies. Compared to the control group, the breathing exercise group exhibited significantly improved lung function (FVC%pred: MD  =  3.46, 95%CI = 1.04 to 5.88; DLCO%pred: MD = 3.20, 95% CI = 2.91 to 3.48), dyspnoea (MRC or mMRC scale: MD = - 0.50, 95%CI = - 0.77 to - 0.22), exercise capacity (6MWD: MD = 32.65, 95% CI = 14.77 to 50.53), and HRQoL (SGRQ: MD = - 6.53, 95% CI = - 8.72 to - 4.34) in ILD patients. According to the subgroup analysis, significant improvements consistent with the overall results were observed in the control group with usual treatment. Compared with the control group, breathing exercises had varying degrees of improvement in the mixed diagnostic group, known-cause group, and fibrotic group of ILD patients; breathing exercises alone significantly improved DLCO%pred, MRC (or mMRC), and SGRQ; and the improvement in breathing exercises as part of pulmonary rehabilitation (PR) was more notable. Different durations of breathing exercise could promote the efficacy of different aspects of treatment for ILD patients.

conclusionsCompared with usual treatment, breathing exercises can improve lung function, exercise capacity, and HRQoL in ILD patients, particularly without high requirements for intervention duration. The efficacy of breathing exercises varies for different ILD subtypes, and incorporating breathing exercises as part of PR can be more beneficial for ILD patients. No studies have shown significant risks for ILD patients engaging in breathing exercises.

Indexed as

Breathing ExercisesLung Diseases, InterstitialQuality of LifeExercise ToleranceHumansRespiratory Function TestsTreatment OutcomeBreathing exercisesInterstitial lung diseaseMeta-analysisSystematic review

Identifiers

PMID38907831

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.