Evidence map›Paper›PMID 38907797›Full record

SynthesisUrolithiasis2024

Predictive value of inflammatory markers for the spontaneous passage of Ureteral stones: a comprehensive systematic review with meta analysis.

Rawa Bapir, Saman S Fakhralddin, Ismaeel Aghaways, Bryar O Muhammed, Hawbash M Rahim, Fattah H Fattah, Barzan O Ismael, Rebaz E Ali, Karokh F Hamahussein, Fahmi Hussein Kakamad and 3 more

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Urolithiasis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Ethnic diversity and urolithiasis: a single-center experience.International urology and nephrology · 2025
    Article
  4. Evaluating blood and urinary markers for prediction of spontaneous ureteral stone passage.American journal of clinical and experimental urology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Rawa BapirDepartment of Urology, Sulaymaniyah Surgical Teaching Hospital, Sulaymaniyah, 46001, Iraq.
Saman S FakhralddinDepartment of Urology, Sulaymaniyah Surgical Teaching Hospital, Sulaymaniyah, 46001, Iraq.
Ismaeel AghawaysCollege of Medicine, University of Sulaimani, Madam Mitterrand Street, Sulaimani, Kurdistan, 46001, Iraq.
Bryar O MuhammedScientific Affairs Department, Smart Health Tower/Raparin, Sarkapkan Street, Sulaimani, Kurdistan, 46001, Iraq.
Hawbash M RahimKscien Organization for Scientific Research, Hamdi Street, Azadi Mall, Sulaimani, Kurdistan, 46001, Iraq.
Fattah H FattahScientific Affairs Department, Smart Health Tower, Madam Mitterrand Street, Sulaimani, Kurdistan, 46001, Iraq.
Barzan O IsmaelScientific Affairs Department, Smart Health Tower/Raparin, Sarkapkan Street, Sulaimani, Kurdistan, 46001, Iraq.
Rebaz E AliScientific Affairs Department, Smart Health Tower, Madam Mitterrand Street, Sulaimani, Kurdistan, 46001, Iraq.
Karokh F HamahusseinScientific Affairs Department, Smart Health Tower, Madam Mitterrand Street, Sulaimani, Kurdistan, 46001, Iraq.
Fahmi Hussein KakamadScientific Affairs Department, Smart Health Tower, Madam Mitterrand Street, Sulaimani, Kurdistan, 46001, Iraq. fahmi.hussein@univsul.edu.iq.
Rawezh Q SalihScientific Affairs Department, Smart Health Tower, Madam Mitterrand Street, Sulaimani, Kurdistan, 46001, Iraq.
Shvan H MohammedKscien Organization for Scientific Research, Hamdi Street, Azadi Mall, Sulaimani, Kurdistan, 46001, Iraq.
Berun A AbdallaScientific Affairs Department, Smart Health Tower, Madam Mitterrand Street, Sulaimani, Kurdistan, 46001, Iraq.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urolithiasis is a common disease that affects approximately one-fifth of the global population. This systematic review explores the predictive role of inflammatory markers for the spontaneous passage of ureteral stones. The literature was systematically searched via Google Scholar, PubMed/MEDLINE, the Cochrane Library, Science Direct, CINAHL, Web of Science, and EMBASE databases to identify papers published until 2023. Overall, 26 articles were identified, of which 10 were excluded. The remaining 16 papers reported 2,695 patients (1,723 males and 972 females), with 1,654 (61.37%) experiencing spontaneous stone passage (SSP) and 1,041 (38.63%) not experiencing it (non-SSP). Stones located in the upper part of the ureter were less likely to pass spontaneously (152/959, 15.94% in the SSP group vs. 180/546, 32.48% in the non-SSP group; p < 0.001). Mid-ureteral stones were present in 180/959 (18.75%) of the SSP group compared to 84/546 (14.52%) of the non-SSP group (p = 0.0974). Lower ureteral stones were more likely to pass spontaneously, with 627/959 (63.31%) in the SSP group compared to 282/546 (49.36%) in the non-SSP group (p < 0.001). No significant correlation was found between most inflammatory markers and SSP (p > 0.05). However, procalcitonin levels were lower in the SSP group compared to the non-SSP group (132.7 ± 28.1 vs. 207 ± 145.1, respectively) (p < 0.001). This systematic review has revealed that except procalcitonin, most inflammatory markers do not offer significant predictive capability for ureteral SSP.

Indexed as

BiomarkersPredictive Value of TestsUreteral CalculiHumansInflammationRemission, SpontaneousBiomarkersInflammatory markersProcalcitoninUreterUrolithiasis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.