Evidence map›Paper›PMID 38907791›Full record

ReviewCurrent pain and headache reports2024

Advances in the Treatment of Neuropathic Pain by Sympathetic Regulation.

Ping Xu, Han Rui Fan, En Ming Zhang, Hao Nan Zhang, Yong Fei

Abstract readReview
In one paragraph

Review in Current pain and headache reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Tumor Innervation: From Bystander to Emerging Therapeutic Target for Cancer.International journal of molecular sciences · 2025
    Review
  9. Emerging role of macrophages in neuropathic pain.Journal of orthopaedic translation · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ping XuZhejiang Chinese Medical University, Hangzhou, Zhejiang, People's Republic of China.
Han Rui FanZhejiang Chinese Medical University, Hangzhou, Zhejiang, People's Republic of China.
En Ming ZhangZhejiang Chinese Medical University, Hangzhou, Zhejiang, People's Republic of China.
Hao Nan ZhangJiaxing University, Jiaxing, Zhejiang, People's Republic of China.
Yong FeiDepartment of Anesthesiology and Pain, The First Hospital of Jiaxing, Jiaxing, Zhejiang, People's Republic of China. jxfy6666662022@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewTo explore the mechanism and therapeutic effect of sympathetic nerve regulation on neuropathic pain. RECENT

findingsA comprehensive search was conducted in the PubMed and CNKI libraries, using the following keywords: stele ganglion block, neuropathic pain, sympathetic nerve block, sympathetic chemical destruction, and sympathetic radiofrequency thermocoagulation. We selected and critically reviewed research articles published in English that were related to sympathetic modulation in the treatment of neuropathic pain. The collected literature will be classified according to content and reviewed in combination with experimental results and clinical cases. Neuropathic pain was effectively treated with sympathetic regulation technology. Its mechanism includes the inhibition of sympathetic nerve activity, regulation of the inflammatory response, and inhibition of pain transmission, which greatly alleviates neuropathic pain in patients. Stellate ganglion blocks, thoracic and lumbar sympathectomies, chemical destruction, and radiofrequency thermocoagulation have been widely used to treat neuropathic pain. Sympathetic regulation can effectively relieve pain symptoms and improve the patient's quality of life by inhibiting sympathetic nerve activity, reducing the production and release of pain-related mediators, and inhibiting pain transmission. CT-guided radiofrequency thermocoagulation of the thoracic and lumbar sympathetic nerves is effective and durable, with few complications, and is recommended as a treatment for intractable neuropathic pain.

Indexed as

Autonomic Nerve BlockNeuralgiaElectrocoagulationHumansStellate GanglionSympathectomySympathetic Nervous SystemNeuropathic painStellate ganglion blockSympathetic radiofrequency thermocoagulationSympathetic regulation

Identifiers

PMID38907791
PMCPMC11461765

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.