Evidence map›Paper›PMID 38907125›Full record

ArticleReproductive sciences (Thousand Oaks, Calif.)2024

Maternal Uterine Artery Adenoviral Vascular Endothelial Growth Factor (Ad.VEGF-A

M D Hristova, T Krishnan, C A Rossi, J Nouza, A White, D M Peebles, N J Sebire, I C Zachary, A L David, O R Vaughan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Reproductive sciences (Thousand Oaks, Calif.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

M D HristovaElizabeth Garrett Anderson Institute for Women's Health, 86-96 Chenies Mews, University College London, London, WC1E 6HX, UK.
T KrishnanElizabeth Garrett Anderson Institute for Women's Health, 86-96 Chenies Mews, University College London, London, WC1E 6HX, UK.
C A RossiElizabeth Garrett Anderson Institute for Women's Health, 86-96 Chenies Mews, University College London, London, WC1E 6HX, UK.
J NouzaElizabeth Garrett Anderson Institute for Women's Health, 86-96 Chenies Mews, University College London, London, WC1E 6HX, UK.
A WhiteBiological Services Unit, Royal Veterinary College, London, UK.
D M PeeblesElizabeth Garrett Anderson Institute for Women's Health, 86-96 Chenies Mews, University College London, London, WC1E 6HX, UK.
N J SebireGreat Ormond Street Institute of Child Health, University College London, London, UK.
I C ZacharyCentre for Cardiovascular Biology and Medicine, Division of Medicine, University College London, London, UK.
A L DavidElizabeth Garrett Anderson Institute for Women's Health, 86-96 Chenies Mews, University College London, London, WC1E 6HX, UK.
O R VaughanElizabeth Garrett Anderson Institute for Women's Health, 86-96 Chenies Mews, University College London, London, WC1E 6HX, UK. o.vaughan@ucl.ac.uk.ORCID 0000-0001-7537-3264

Funding

Action Medical Research SP2169
6 · The paper itself

Abstract

Fetal growth restriction (FGR) is associated with uteroplacental insufficiency, and neurodevelopmental and structural brain deficits in the infant. It is currently untreatable. We hypothesised that treating the maternal uterine artery with vascular endothelial growth factor adenoviral gene therapy (Ad.VEGF-A

Indexed as

AdenoviridaeBrainFetal Growth RetardationGenetic TherapyMicrogliaUterine ArteryVascular Endothelial Growth Factor AAnimalsFemaleFetal DevelopmentGenetic VectorsGuinea PigsPregnancyVascular Endothelial Growth Factor ACerebral palsyGlial fibrillary astrocytic proteinIonized calcium binding adapter molecule 1 proteinPlacentaPre-eclampsia

Identifiers

PMID38907125
PMCPMC11289362

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.