Evidence map›Paper›PMID 38907124›Full record

Observational studyMolecular imaging and biology2024

Optimizing SUV Analysis: A Multicenter Study on Preclinical FDG-PET/CT Highlights the Impact of Standardization.

Claudia Kuntner, Carlos Alcaide, Dimitris Anestis, Jens P Bankstahl, Herve Boutin, David Brasse, Filipe Elvas, Duncan Forster, Maritina G Rouchota, Adriana Tavares and 4 more

Abstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Molecular imaging and biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Applications of artificial intelligence in nuclear medicine.Zeitschrift fur medizinische Physik · 2026
    Review
  2. Article
  3. Review
  4. First human whole-body biodistribution and dosimetry analysis of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Claudia KuntnerDepartment of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Vienna, Austria. claudia.kuntner@meduniwien.ac.at.ORCID 0000-0002-5988-1434
Carlos AlcaideUniversity of Edinburgh, Edinburgh, UK.
Dimitris AnestisBIOEMTECH, Athens, Greece.
Jens P BankstahlHannover Medical School, Hannover, Germany.
Herve BoutinDivision of Neuroscience & Experimental Psychology, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
David BrasseInstitut Pluridisciplinaire Hubert Curien, UMR7178, Université de Strasbourg, CNRS, Strasbourg, France.
Filipe ElvasMolecular Imaging Center Antwerp, University of Antwerpen, Antwerp, Belgium.
Duncan ForsterDivision of Informatics, Imaging and Data Sciences, Manchester Molecular Imaging Centre, The University of Manchester, Manchester, UK.
Maritina G RouchotaBIOEMTECH, Athens, Greece.
Adriana TavaresUniversity of Edinburgh, Edinburgh, UK.
Mari TeuterHannover Medical School, Hannover, Germany.
Thomas WanekDepartment of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Vienna, Austria.
Lena ZachhuberDepartment of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Vienna, Austria.
Julia G MannheimDepartment of Preclinical Imaging and Radiopharmacy Werner Siemens Imaging Center, Eberhard-Karls University Tuebingen, Tuebingen, Germany.

Funding

Chan Zuckerberg Initiative 2023-321161European Cooperation in Science and Technology CA17121
6 · The paper itself

Abstract

purposePreclinical imaging, with translational potential, lacks a standardized method for defining volumes of interest (VOIs), impacting data reproducibility. The aim of this study was to determine the interobserver variability of VOI sizes and standard uptake values (SUV PROCEDURES: In total, 12 observers (4 beginners and 8 experts) analyzed identical preclinical [

resultsWithout standardization, significant differences in the SUV

conclusionsThe protocol offered clear guidelines and was particularly beneficial for beginners, resulting in improved comparability of SUV

Indexed as

Fluorodeoxyglucose F18Observer VariationPositron Emission Tomography Computed TomographyAnimalsHumansImage Processing, Computer-AssistedReference StandardsReproducibility of ResultsFluorodeoxyglucose F18Image analysisMulticenterPET/CTPreclinical imagingReproducibility

Identifiers

PMID38907124
PMCPMC11281957

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.