Evidence map›Paper›PMID 38907089›Full record

ReviewJournal of ultrasound2024

Skeletal muscle as a pro- and anti-inflammatory tissue: insights from children to adults and ultrasound findings.

Armando Di Ludovico, Saverio La Bella, Francesca Ciarelli, Francesco Chiarelli, Luciana Breda, Angelika Mohn

Abstract readReview
In one paragraph

Review in Journal of ultrasound, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Review
  3. Association of muscle strength with abdominal aortic calcification.The Journal of international medical research · 2026
    Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Observational
  14. Article
  15. Review
  16. Observational
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Armando Di LudovicoDepartment of Pediatrics, University of Chieti, Chieti, Italy. armandodl@outlook.com.ORCID http://orcid.org/0000-0002-2644-1475
Saverio La BellaDepartment of Pediatrics, University of Chieti, Chieti, Italy.
Francesca CiarelliDepartment of Pediatrics, University of Chieti, Chieti, Italy.
Francesco ChiarelliDepartment of Pediatrics, University of Chieti, Chieti, Italy.
Luciana BredaDepartment of Pediatrics, University of Chieti, Chieti, Italy.
Angelika MohnDepartment of Pediatrics, University of Chieti, Chieti, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previously regarded as a movement and posture control agent, the skeletal muscle is now recognized as an endocrine organ that may affect systemic inflammation and metabolic health. The discovery of myokines such as IL-6, released from skeletal muscle in response to physical exercise, is now one of the most recent insights. Myokines are the mediators of the balance between the pro-inflammatory and anti-inflammatory responses. This underscores the muscle function as a determinant of good health and prevention of diseases. Advances in ultrasound technology improved evaluation of muscle thickness, composition, and determining fat distribution. Combining imaging with molecular biology, researchers discovered the complicated interplay between muscle function, cytokine production and general health effects.The production of myokines with exercise showcasing the adaptability of muscles to high-stress conditions and contributing to metabolism and inflammation regulation. These findings have significant implications in order to provide improvement in metabolic and inflammatory diseases.

Indexed as

InflammationMuscle, SkeletalUltrasonographyAdultChildCytokinesExerciseHumansCytokinesAdipokinesInflammationMyokinesObesityUltrasound

Identifiers

PMID38907089
PMCPMC11496437

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.