Evidence map›Paper›PMID 38907067›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2024

Impact of age on comparative outcomes of decompression alone versus fusion for L4 degenerative spondylolisthesis.

Pratyush Shahi, Sumedha Singh, Kyle Morse, Omri Maayan, Tejas Subramanian, Kasra Araghi, Nishtha Singh, Olivia C Tuma, Tomoyuki Asada, Maximilian K Korsun and 6 more

Abstract readComparative Study
In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Pratyush ShahiDepartment of Spine Surgery, Hospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
Sumedha SinghDepartment of Spine Surgery, Hospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
Kyle MorseDepartment of Spine Surgery, Hospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
Omri MaayanDepartment of Spine Surgery, Hospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
Tejas SubramanianDepartment of Spine Surgery, Hospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
Kasra AraghiDepartment of Spine Surgery, Hospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
Nishtha SinghDepartment of Spine Surgery, Hospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
Olivia C TumaDepartment of Spine Surgery, Hospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
Tomoyuki AsadaDepartment of Spine Surgery, Hospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
Maximilian K KorsunDepartment of Spine Surgery, Hospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
James DowdellDepartment of Spine Surgery, Hospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
Evan D ShehaDepartment of Spine Surgery, Hospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
Harvinder SandhuDepartment of Spine Surgery, Hospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
Todd J AlbertDepartment of Spine Surgery, Hospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
Sheeraz A QureshiDepartment of Spine Surgery, Hospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.
Sravisht IyerDepartment of Spine Surgery, Hospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA. iyers@hss.edu.ORCID http://orcid.org/0000-0002-8338-9757

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
NCATS NIH HHS UL1 TR001873NCATS NIH HHS UL1 TR002384
6 · The paper itself

Abstract

purposeTo compare the outcomes of decompression alone and fusion for L4-5 DLS in different age cohorts (< 70 years, ≥ 70 years).

methodsThis retrospective cohort study included patients who underwent minimally invasive decompression or fusion for L4-5 DLS and had a minimum of 1-year follow-up. Outcome measures were: (1) patient-reported outcome measures (PROMs) (Oswestry Disability Index, ODI; Visual Analog Scale back and leg, VAS; 12-Item Short Form Survey Physical Component Score, SF-12 PCS), (2) minimal clinically important difference (MCID), (3) patient acceptable symptom state (PASS), (4) response on the global rating change (GRC) scale, and (5) complication rates. The decompression and fusion groups were compared for outcomes separately in the < 70-year and ≥ 70-year age cohorts.

results233 patients were included, out of which 52% were < 70 years. Patients < 70 years showed non-significant improvement in SF-12 PCS and significantly lower MCID achievement rates for VAS back after decompression compared to fusion. Analysis of the ≥ 70-year age cohort showed no significant differences between the decompression and fusion groups in the improvement in PROMs, MCID/PASS achievement rates, and responses on GRC. Patients ≥ 70 years undergoing fusion had significantly higher in-hospital complication rates. When analyzed irrespective of the surgery type, both < 70-year and ≥ 70-year age cohorts showed significant improvement in PROMs with no significant difference.

conclusionsPatients < 70 years undergoing decompression alone did not show significant improvement in physical function and had significantly less MCID achievement rate for back pain compared to fusion. Patients ≥ 70 years showed no difference in outcomes between decompression alone and fusion.

Indexed as

Decompression, SurgicalLumbar VertebraeSpinal FusionSpondylolisthesisAgedAged, 80 and overAge FactorsFemaleHumansMaleMiddle AgedPatient Reported Outcome MeasuresRetrospective StudiesTreatment OutcomeAgeAssociationDecompressionDegenerative spondylolisthesisFusionOlderOutcomesYounger

Identifiers

PMID38907067
PMCPMC11780706

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.