SynthesisEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2024
Impact of sarcopenia on outcomes following lumbar spine surgery for degenerative disease: an updated systematic review and meta-analysis.
Synthesis in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Radiographic paraspinal muscle size in adult spinal deformity: a systematic review and meta-analysis.Spine deformity · 2026Pooled it
- The Added Value and the Efficacy of Preoperative Physiotherapy on Degenerative Diseases of the Lumbar Spine: A Systematic Review.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026Pooled it
- Sarcopenia and related musculoskeletal phenotypes in patients considered for spinal cord stimulation: a scoping review.Frontiers in medicine · 2026Pooled it
- Does pre-operative psoas muscle cross-sectional area predict post-operative outcomes following lumbar spine fusion surgery?-a systematic review and narrative synthesis.Journal of spine surgery (Hong Kong) · 2026Review
- Preoperative BMI-adjusted sarcopenia defined by AWGS 2025 is associated with 1-year changes in the patient-reported outcomes of lumbar spinal stenosis surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Association of glucagon-like peptide-1 receptor agonist use with patient-reported outcomes after lumbar decompression or fusion.North American Spine Society journal · 2026Article
- Frailty-Muscle Phenotypes Predict Outcomes After Lumbar Fusion in Adults Aged ≥75 Years: A Retrospective Cohort Study.Neurospine · 2026Article
- Effect of sarcopenia and paraspinal muscle morphology on conservative treatment outcomes in lumbar spinal stenosis: a prospective cohort study.Frontiers in aging · 2026Article
- From Incision to Prescription: Unraveling Pain and Opioid Use in Adult Spinal Deformity Surgery.International journal of spine surgery · 2025Article
- Answer to the letter to the editor of K. Zhou et al. concerning "early functional training is not superior to routine rehabilitation in improving walking distance and multifidus atrophy after lumbar fusion: a randomized controlled trial with 6-month follow-up" by Lu H, et al. (Eur spine J [2025]: doi: 10.1007/s00586-025-08771-7).European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Impact of sarcopenia on outcomes following vertebral augmentation for osteoporotic vertebral compression fracture: a systematic review and meta-analysis.Asian spine journal · 2025Article
- Malnutrition and Disability: A Retrospective Study on 2258 Adult Patients Undergoing Elective Spine Surgery.Medicina (Kaunas, Lithuania) · 2025Observational
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to consolidate the evidence regarding the prognostic influence of sarcopenia in degenerative lumbar spine surgeries.
methodsA literature search of public databases was conducted up to Nov 15, 2023 using combinations of the key words "sarcopenia" and "lumbar spine surgery". Eligible studies were those that focused on adults undergoing decompression or fusion surgery for degenerative lumbar spine diseases, and compared the outcomes between patients with and without preoperative sarcopenia. Primary outcomes were change in ODI and back and leg pain VAS pain scores. Secondary outcomes were changes in Eq. 5D, JOA, SFHS-p scores, and LOS.
resultsUltimately, nine retrospective studies with a total of 993 patients were included. Sarcopenic patients exhibited significantly worse functional improvement as assessed by ODI compared to non-sarcopenic patients (pooled standardized mean difference [pSMD] = 0.53, 95% confidence interval [CI]: 0.17-0.90). Back pain (pSMD = 0.31, 95% CI:0.15-0.47) and leg pain (pSMD = 0.21, 95% CI:0.02 - 0.39) improvement were also less in sarcopenic patients. Non-sarcopenic patients had greater improvements in Eq. 5D (pSMD = 0.25) and SFHS-p (pSMD = 0.39), and shorter LOS (pSMD = 0.62).
conclusionsAs compared to patients without sarcopenia, those with sarcopenia undergoing lumbar spine surgery for degenerative diseases have lower improvements in functional ability, quality of life, physical health, pain relief and extended hospitalization compared to those without sarcopenia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.