Evidence map›Paper›PMID 38906929›Full record

ArticleScientific reports2024

CD248-expressing cancer-associated fibroblasts induce epithelial-mesenchymal transition of non-small cell lung cancer via inducing M2-polarized macrophages.

Jing Xiao, Zeyang Yang, Siyu Wang, Xinlei Liu, Yun Wang, Zuquan Hu, Zhu Zeng, Jieheng Wu

Erratum issuedAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Jing Xiao *Department of Immunology, Guizhou Medical University, Siya Road, Guiyang, 561113, China.
Zeyang Yang *Department of Immunology, Guizhou Medical University, Siya Road, Guiyang, 561113, China.
Siyu Wang *Department of Immunology, Guizhou Medical University, Siya Road, Guiyang, 561113, China.
Xinlei LiuGuizhou Prenatal Diagnosis Center, The Affiliated Hospital of Guizhou Medical University, Guiyang, 550001, China.
Yun WangDepartment of Immunology, Guizhou Medical University, Siya Road, Guiyang, 561113, China.
Zuquan HuImmune Cells and Antibody Engineering Research Center of Guizhou Province, Key Laboratory of Biology and Medical Engineering, Guizhou Medical University, Guiyang, 561113, China.
Zhu ZengDepartment of Immunology, Guizhou Medical University, Siya Road, Guiyang, 561113, China. zengzhu@gmc.edu.cn.
Jieheng WuDepartment of Immunology, Guizhou Medical University, Siya Road, Guiyang, 561113, China. immunewjh@163.com.

Funding

Flexible Talent Introduction Project of Guizhou Medical University RN2021-GK045National Natural Science Foundation of China 12132006National Natural Science Foundation of China 82160566National Natural Science Foundation of China Cultivation Program of Guizhou Medical University 20NSP002
6 · The paper itself

Abstract

Non-small cell lung cancer (NSCLC)-originating cancer-associated fibroblasts (CAFs) expressing CD248 regulate interaction with immune cells to accelerate cancer progression. Epithelial-mesenchymal transition (EMT) is a key feature of metastatic cells. In our pervious study, we found that CD248

Indexed as

Antigens, CDCancer-Associated FibroblastsCarcinoma, Non-Small-Cell LungEpithelial-Mesenchymal TransitionLung NeoplasmsMacrophagesAnimalsAntigens, NeoplasmCell Line, TumorHumansMiceMice, KnockoutAntigens, CDAntigens, NeoplasmCD248 protein, humanCancer-associated fibroblastsCD248EMTM2 macrophagesNon-small cell lung cancer

Identifiers

PMID38906929
PMCPMC11192924

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.