Evidence map›Paper›PMID 38906685›Full record

ArticleJournal of neurointerventional surgery2025

Placing the balloon-guide catheter in the high cervical segment of the internal carotid artery is associated with improved recanalization.

Manuel Moreu, Carlos Gómez-Escalonilla, Salvador Miralbes, Bharath Naravetla, Alejandro M Spiotta, Christian Loehr, Mario Martínez-Galdámez, Ryan A McTaggart, Luc Defreyne, Pedro Vega and 7 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of neurointerventional surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Manuel MoreuRadiology department, Neurointerventional unit, Hospital Clinico Universitario San Carlos, Madrid, Spain manumoreu@gmail.com.ORCID http://orcid.org/0000-0002-9001-0661
Carlos Gómez-EscalonillaNeurology Department, Hospital Clínico San Carlos, Madrid, Comunidad de Madrid, Spain.
Salvador MiralbesNeuroradiology, Hospital Universitari Son Espases, Palma de Mallorca, Illes Balears, Spain.
Bharath NaravetlaMcLaren Regional Medical Center, Flint, Michigan, USA.
Alejandro M SpiottaNeurosurgery, Medical University of South Carolina, Charleston, South Carolina, USA.ORCID http://orcid.org/0000-0002-7142-5538
Christian LoehrDepartment of Radiology and Neuroradiology, Klinikum Vest GmbH, Recklinghausen, Nordrhein-Westfalen, Germany.
Mario Martínez-GaldámezInterventional Neuroradiology/Endovascular Neurosurgery, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.ORCID http://orcid.org/0000-0002-8024-4712
Ryan A McTaggartRhode Island Hospital, Providence, Rhode Island, USA.
Luc DefreyneInterventional Neuroradiology, University Hospital Ghent, Ghent, Belgium.ORCID http://orcid.org/0000-0001-5814-2798
Pedro VegaRadiology, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain.ORCID http://orcid.org/0000-0002-7446-4540
Osama O ZaidatNeuroscience, St Vincent Mercy Hospital, Toledo, Ohio, USA.ORCID http://orcid.org/0000-0003-4881-4698
Lori Lyn PriceClinical Affairs, Stryker Neurovascular, Fremont, California, USA.
David S LiebeskindNeurology, UCLA, Los Angeles, California, USA.ORCID http://orcid.org/0000-0002-5109-8736
Markus A MöhlenbruchNeuroradiology, Heidelberg University, Heidelberg, Baden-Württemberg, Germany.
Rishi GuptaWellstar Health System Inc, Marietta, Georgia, USA.
Santiago RosatiRadiology department, Neurointerventional unit, Hospital Clinico Universitario San Carlos, Madrid, Spain.
ASSIST Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMechanical thrombectomy (MT) is part of the standard of care for stroke treatment, and improving its efficacy is one of the main objectives of clinical investigation. Of importance is placement of the distal end of balloon-guided catheters (BGC). We aim to determine if this influences outcomes.

methodsWe analyzed data from the ASSIST Registry, an international, multicenter prospective study of 1492 patients. We divided patients treated with BGC according to the placement of the BGC: low cervical (LCG (the lower 2/3 of cervical internal carotid artery (ICA)) or high cervical (HCG (upper 1/3 of cervical ICA, petro-lacerum or higher)). We analyzed characteristics and outcomes overall and stratified on the primary MT technique: Stent-Retriever only (SR Classic), Combined use of aspiration catheter and SR (Combined), and Direct Aspiration (ADAPT).

resultsOur study included 704 subjects -323 in the low cervical and 381 in the high cervical groups. Statistical differences were seen in the proportion of females and tandem lesions (both higher for LCG). Placing the BGC in the high cervical segment is associated with better recanalization rates (expanded treatment in cerebral infarction (eTICI) score of 2c-3) at the end of the procedure (P<0.0001) and shorter procedures (P=0.0005). After stratifying on the three primary techniques (SR Classic, Combined, and ADAPT), placing the BGC in the high segment is associated with a better first-pass effect (FPE), less distal emboli, and better clinical outcomes in the SR Classic technique.

conclusionsPlacing the distal end of the BGC at the high cervical segment or higher is associated with better recanalization.

Indexed as

Carotid Artery, InternalThrombectomyAgedAged, 80 and overFemaleHumansMaleMiddle AgedProspective StudiesRegistriesTreatment OutcomeBalloonCatheterStrokeTechniqueThrombectomy

Identifiers

PMID38906685
PMCPMC12171514

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.