Evidence map›Paper›PMID 38906561›Full record

Observational studyBMJ paediatrics open2024

Morbidity and unplanned healthcare encounters after hospital discharge among young children in Dar es Salaam, Tanzania and Monrovia, Liberia.

Rodrick Kisenge, Readon C Ideh, Julia Kamara, Ye-Jeung G Coleman-Nekar, Abraham Samma, Evance Godfrey, Hussein K Manji, Christopher R Sudfeld, Adrianna Westbrook, Michelle Niescierenko and 6 more

Abstract readObservational Study
In one paragraph

Observational study in BMJ paediatrics open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Rodrick KisengeDepartment of Paediatrics and Child Health, Muhimbili University of Health and Allied Sciences, Dar es Salaam, United Republic of Tanzania saroriki@yahoo.com.
Readon C IdehDepartment of Pediatrics, John F. Kennedy Medical Center, Monrovia, Liberia.
Julia KamaraDepartment of Pediatrics, John F. Kennedy Medical Center, Monrovia, Liberia.
Ye-Jeung G Coleman-NekarDepartment of Pediatrics, John F. Kennedy Medical Center, Monrovia, Liberia.
Abraham SammaDepartment of Paediatrics and Child Health, Muhimbili University of Health and Allied Sciences, Dar es Salaam, United Republic of Tanzania.
Evance GodfreyDepartment of Paediatrics and Child Health, Muhimbili University of Health and Allied Sciences, Dar es Salaam, United Republic of Tanzania.
Hussein K ManjiAccident and Emergency Department, Aga Khan Health Services, Dar es Salaam, United Republic of Tanzania.
Christopher R SudfeldDepartments of Nutrition and Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Adrianna WestbrookPediatric Biostatistics Core, Department of Pediatrics, Emory University, Atlanta, Georgia, USA.
Michelle NiescierenkoDivision of Emergency Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.
Claudia R MorrisDivision of Pediatric Emergency Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Cynthia G WhitneyEmory Global Health Institute, Emory University, Atlanta, Georgia, USA.
Robert F BreimanHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Christopher P DugganDepartments of Nutrition and Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Karim P ManjiDepartment of Paediatrics and Child Health, Muhimbili University of Health and Allied Sciences, Dar es Salaam, United Republic of Tanzania.
Chris A ReesDivision of Pediatric Emergency Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID http://orcid.org/0000-0001-6449-0377

Funding

Patient-Oriented Research in Arginine Deficiency SyndromesK24AT009893 · NCCIH · EMORY UNIVERSITY · PI Claudia R Morris · 2018 to 2026
$1.5M
Advancing Approaches to Identify Young Children at Risk for Post-Discharge MortalityK23HL173694 · NHLBI · EMORY UNIVERSITY · PI Christopher A. Rees · 2024 to 2026
$585k
NCCIH NIH HHS K24 AT009893NHLBI NIH HHS K23 HL173694
6 · The paper itself

Abstract

backgroundResearchers and healthcare providers have paid little attention to morbidity and unplanned healthcare encounters for children following hospital discharge in low- and middle-income countries. Our objective was to compare symptoms and unplanned healthcare encounters among children aged <5 years who survived with those who died within 60 days of hospital discharge through follow-up phone calls.

methodsWe conducted a secondary analysis of a prospective observational cohort of children aged <5 years discharged from neonatal and paediatric wards of two national referral hospitals in Dar es Salaam, Tanzania and Monrovia, Liberia. Caregivers of enrolled participants received phone calls 7, 14, 30, 45, and 60 days after hospital discharge to record symptoms, unplanned healthcare encounters, and vital status. We used logistic regression to determine the association between reported symptoms and unplanned healthcare encounters with 60-day post-discharge mortality.

resultsA total of 4243 participants were enrolled and had 60-day vital status available; 138 (3.3%) died. For every additional symptom ever reported following discharge, there was a 35% greater likelihood of post-discharge mortality (adjusted odds ratio [aOR] 1.35, 95% confidence interval [CI] 1.10 to 1.66; p=0.004). The greatest survival difference was noted for children who had difficulty breathing (2.1% among those who survived vs 36.0% among those who died, p<0.001). Caregivers who took their child home from the hospital against medical advice during the initial hospitalisation had over eight times greater odds of post-discharge mortality (aOR 8.06, 95% CI 3.87 to 16.3; p<0.001) and those who were readmitted to a hospital had 3.42 greater odds (95% CI 1.55 to 8.47; p=0.004) of post-discharge mortality than those who did not seek care when adjusting for site, sociodemographic factors, and clinical variables.

conclusionSurveillance for symptoms and repeated admissions following hospital discharge by healthcare providers is crucial to identify children at risk for post-discharge mortality.

Indexed as

Patient DischargeChild, PreschoolFemaleHumansInfantInfant, NewbornLiberiaMaleMorbidityPatient Acceptance of Health CareProspective StudiesTanzaniaChild HealthInfantMortality

Identifiers

PMID38906561
PMCPMC11191828

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.