Evidence map›Paper›PMID 38906224›Full record

ArticleJournal of affective disorders2024

Examining time-varying dynamics of co-occurring depressed mood and anxiety.

Marilyn L Piccirillo, Madelyn R Frumkin, Katie Malloy Spink, Natasha A Tonge, Katherine T Foster

Abstract read
In one paragraph

Article in Journal of affective disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marilyn L PiccirilloUniversity of Washington, Department of Psychology, United States of America; Rutgers Robert Wood Johnson Medical School, Department of Psychiatry, United States of America. Electronic address: Marilyn.piccirillo@rutgers.edu.
Madelyn R FrumkinWashington University in St. Louis, Department of Psychology and Brain Sciences, United States of America; Massachusetts General Hospital, Department of Psychiatry, United States of America.
Katie Malloy SpinkUniversity of Washington, Department of Psychology, United States of America.
Natasha A TongeGeorge Mason University, Department of Psychology, United States of America.
Katherine T FosterUniversity of Washington, Department of Psychology, United States of America; University of Washington, Department of Global Health, United States of America.

Funding

Psychology Training in Alcohol Research (PTAR)T32AA007455 · NIAAA · UNIVERSITY OF WASHINGTON · PI MARY E. LARIMER · 1985 to 2026
$11.4M
Digital Phenotyping of Anxiety and Anxiety-Related Alcohol Comorbidity and TreatmentR00AA029459 · NIAAA · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Marilyn Piccirillo · 2024 to 2026
$727k
Digital Phenotyping of Anxiety and Anxiety-Related Alcohol Comorbidity and TreatmentK99AA029459 · NIAAA · UNIVERSITY OF WASHINGTON · PI PICCIRILLO, MARILYN · 2022 to 2023
$307k
Personalized Models of Depression and Chronic PainF31MH124291 · NIMH · WASHINGTON UNIVERSITY · PI FRUMKIN, MADELYN · 2021 to 2022
$88k
Longitudinal Risk Factors For Depression and Development of Individual Risk ModelsF31MH115641 · NIMH · WASHINGTON UNIVERSITY · PI PICCIRILLO, MARILYN · 2017 to 2018
$74k
NIAAA NIH HHS K99 AA029459NIAAA NIH HHS R00 AA029459NIAAA NIH HHS T32 AA007455NIMH NIH HHS F31 MH115641NIMH NIH HHS F31 MH124291
6 · The paper itself

Abstract

backgroundDimensional frameworks of psychopathology call for multivariate approaches to map co-occurring disorders to index what symptoms emerge when and for whom. Ecological momentary assessment (EMA) offers a method for assessing and differentiating the dynamics of co-occurring symptoms with greater temporal granularity and naturalistic context. The present study used multivariate mixed effects location-scale modeling to characterize the time-varying dynamics of depressed mood and anxiety for women diagnosed with social anxiety disorder (SAD) and major depression (MDD).

methodsWomen completed five daily EMA surveys over 30 days (150 EMA surveys/woman, T ≈ 5250 total observations) and two clinical diagnostic and retrospective self-report measures administered approximately two months apart.

resultsThere was evidence of same-symptom lagged effects (bs = 0.08-0.09), but not cross-symptom lagged effects (bs < 0.01) during EMA. Symptoms co-varied such that momentary spikes from one's typical level of anxiety were associated with increases in momentary depressed mood (b = 0.19) and greater variability of depressed mood (b = 0.06). Similarly, spikes from one's typical levels of depressed mood were associated with increases in momentary anxiety (b = 0.19). Furthermore, the presence and magnitude of effects demonstrated person-specific heterogeneity. LIMITATIONS: Our findings are constrained to the dynamics of depressed and anxious mood among cisgender women with primary SAD and current or past MDD.

conclusionsFindings from this work help to characterize how daily experiences of co-occurring mood and anxiety fluctuate and offer insight to aid the development of momentary, person-specific interventions designed to regulate symptom fluctuations.

Indexed as

Ecological Momentary AssessmentMajor Depressive DisorderAdultAnxietyDepressionFemaleHumansMiddle AgedPhobia, SocialRetrospective StudiesSelf ReportYoung AdultAffective dynamicsEcological momentary assessmentHeterogeneityHiTOPInternalizing

Identifiers

PMID38906224
PMCPMC11316648

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.