Evidence map›Paper›PMID 38905769›Full record

ArticleThe Journal of surgical research2024

Clinical Signs as a Guide for Esophagram After Esophageal Atresia/Tracheoesophageal Fistula Repair.

Devashish Joshi, Michael Stellon, Keon Young Park, Jessica Hellner, Hau D Le

Abstract read
In one paragraph

Article in The Journal of surgical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Devashish JoshiDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Michael StellonDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Keon Young ParkDepartment of Surgery, University of California San Diego, La Jolla, California.
Jessica HellnerDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Hau D LeDepartment of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin. Electronic address: leh@surgery.wisc.edu.

Funding

Training Program in Translational Cardiovascular Science (TPTCS)T32HL007936 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI Lee Lochbaum Eckhardt, Gail A Robertson · 2001 to 2026
$11.6M
Predicting Future Liver Remnant Function and Growth Trajectory Using Novel MR Imaging BiomarkersF32CA284535 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI JOSHI, DEVASHISH · 2023 to 2023
$70k
NCI NIH HHS F32 CA284535NHLBI NIH HHS T32 HL007936
6 · The paper itself

Abstract

introductionEsophageal atresia/tracheoesophageal fistula (EA/TEF) is a congenital malformation that occurs in about 1 in 2500-4000 live births. After surgical repair, despite the lack of evidence supporting the routine use of postoperative esophagram, most surgeons report obtaining an esophagram prior to enteral feeding. We hypothesized that abnormal indicators in vital signs, drain characteristics, and chest radiograph (CXR) could be used to screen for anastomotic leak, thus reducing the need for a routine esophagram.

methodsA single institution, retrospective chart review of all patients born with EA with or without TEF between 2009 and 2022 was performed. Vital signs, postoperative CXR, chest drain characteristics, and esophagram results were analyzed for patients who underwent repair.

resultsForty-five patients who underwent EA/TEF repair were included in the study, and 40 patients had routine esophagram. Out of the twenty-two patients who had at least one abnormal indicator, 14 (64%) had an anastomotic leak. Seventeen patients (43%) had the absence of abnormalities of all three indicators, and none of these patients had an anastomotic leak (100% negative predictive value). Moreover, changes in drain characteristics and vital signs together presented high sensitivity (87.5%), specificity (90%), and negative predictive value (94%).

conclusionsIn the absence of abnormalities in vital signs, CXR, and drain characteristics in patients undergoing EA/TEF repair, routine esophagram can be safely avoided prior to enteral feeding. Abnormalities in drain characteristics and vital signs together were highly sensitive and specific for anastomotic leak, thus potentially eliminating the need for routine CXR and thereby minimizing radiation exposure and cost.

Indexed as

Anastomotic LeakEsophageal AtresiaTracheoesophageal FistulaDrainageEsophagusFemaleHumansInfantInfant, NewbornMaleRadiography, ThoracicRetrospective StudiesAnastomotic leakEsophageal atresiaEsophagramTracheoesophageal fistula

Identifiers

PMID38905769
PMCPMC11896690

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.