Evidence map›Paper›PMID 38905237›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Insights into stereoselective ring formation in canonical strigolactone: Identification of a dirigent domain-containing enzyme catalyzing orobanchol synthesis.

Masato Homma, Takatoshi Wakabayashi, Yoshitaka Moriwaki, Nanami Shiotani, Takumi Shigeta, Kazuki Isobe, Atsushi Okazawa, Daisaku Ohta, Tohru Terada, Kentaro Shimizu and 3 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. A dirigent of the ring for strigolactone stereochemistry.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Masato Homma *Department of Agrobioscience, Graduate School of Agricultural Science, Kobe University, Kobe 657-8501, Japan.
Takatoshi Wakabayashi *Department of Agrobioscience, Graduate School of Agricultural Science, Kobe University, Kobe 657-8501, Japan.ORCID 0000-0001-7065-6839
Yoshitaka MoriwakiDepartment of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.
Nanami ShiotaniDepartment of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.ORCID 0000-0002-9429-4657
Takumi ShigetaDepartment of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.
Kazuki IsobeDepartment of Applied Life Sciences, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Sakai 599-8531, Japan.
Atsushi OkazawaDepartment of Applied Life Sciences, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Sakai 599-8531, Japan.
Daisaku OhtaDepartment of Applied Life Sciences, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Sakai 599-8531, Japan.
Tohru TeradaDepartment of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.
Kentaro ShimizuDepartment of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.
Masaharu MizutaniDepartment of Agrobioscience, Graduate School of Agricultural Science, Kobe University, Kobe 657-8501, Japan.ORCID 0000-0002-4321-0644
Hirosato TakikawaDepartment of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan.ORCID 0000-0002-3668-8834
Yukihiro SugimotoDepartment of Agrobioscience, Graduate School of Agricultural Science, Kobe University, Kobe 657-8501, Japan.ORCID 0000-0002-8767-9671

Funding

Japan Agency for Medical Research and Development (AMED) JP22ama121027MEXT | Japan Society for the Promotion of Science (JSPS) 20K15459MEXT | Japan Society for the Promotion of Science (JSPS) 25292065MEXT | JST | ACT-X JPMJAX20BMMEXT | JST | Precursory Research for Embryonic Science and Technology (PRESTO) JPMJPR22DAMEXT | JST | Science and Technology Research Partnership for Sustainable Development (SATREPS) JPMJSA1607
6 · The paper itself

Abstract

Strigolactones (SLs) are plant apocarotenoids with diverse roles and structures. Canonical SLs, widespread and characterized by structural variations in their tricyclic lactone (ABC-ring), are classified into two types based on C-ring configurations. The steric C-ring configuration emerges during the BC-ring closure, downstream of the biosynthetic intermediate, carlactonoic acid (CLA). Most plants produce either type of canonical SLs stereoselectively, e.g., tomato (

Indexed as

LactonesPlant Growth RegulatorsPlant ProteinsSolanum lycopersicumStereoisomerismLactonesorobancholPlant Growth RegulatorsPlant Proteinsbiosynthesisdirigent proteinorobancholstereoselectivity

Identifiers

PMID38905237
PMCPMC11214005

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.