Evidence map›Paper›PMID 38904476›Full record

ArticleOrganic letters2024

Enantioselective Total Syntheses of (+)-Kasugamycin and (+)-Kasuganobiosamine Highlighting a Sulfamate-Tethered

Gour Hari Mandal, Steven P Kelley, Shyam Sathyamoorthi

Abstract read
In one paragraph

Article in Organic letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. TetheredTetrahedron · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gour Hari MandalDepartment of Medicinal Chemistry, University of Kansas, Lawrence, Kansas 66047, United States.
Steven P KelleyDepartment of Chemistry, University of Missouri─Columbia, Columbia, Missouri 65211, United States.ORCID 0000-0001-6755-4495
Shyam SathyamoorthiDepartment of Medicinal Chemistry, University of Kansas, Lawrence, Kansas 66047, United States.ORCID 0000-0003-4705-7349

Funding

Synthetic Chemical Biology CoreP30GM145499 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI Susan M Lunte · 2022 to 2026
$6.9M
Tethered aza-Wacker Technology for Complex Antibiotic AssemblyR35GM142499 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI SATHYAMOORTHI, SHYAM · 2021 to 2025
$1.9M
NIGMS NIH HHS P30 GM145499NIGMS NIH HHS R35 GM142499
6 · The paper itself

Abstract

Here, we present the first enantioselective total syntheses of the natural products (+)-kasugamycin, a potent antifungal antibiotic, and (+)-kasuganobiosamine, a compound that results from the degradation of kasugamycin. Salient features of these syntheses include a second-generation enantioselective preparation of a kasugamine derivative (efficiency much improved relative to that of our first chiral-pool effort) and our laboratory's sulfamate-tethered

Identifiers

PMID38904476
PMCPMC11226349

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.