Evidence map›Paper›PMID 38904409›Full record

ArticleApplied and environmental microbiology2024

Engineering of a TetR family transcriptional regulator BkdR enhances heterologous spinosad production in

Wenzong Wang, Hao Tang, Xingjun Cui, Wenping Wei, Jing Wu, Bang-Ce Ye

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. A new paradigm for the regulation of A40926B0 biosynthesis.Synthetic and systems biotechnology · 2025
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wenzong Wang *Institute of Engineering Biology and Health, Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang, China.
Hao Tang *Institute of Engineering Biology and Health, Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang, China.ORCID 0009-0000-8364-8336
Xingjun CuiInstitute of Engineering Biology and Health, Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang, China.
Wenping WeiInstitute of Engineering Biology and Health, Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang, China.
Jing WuInstitute of Engineering Biology and Health, Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang, China.
Bang-Ce YeInstitute of Engineering Biology and Health, Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang, China.ORCID 0000-0002-5555-5359

Funding

MOST | National Key Research and Development Program of China (NKPs) 2018YFA0900404
6 · The paper itself

Abstract

Precursor supply plays a significant role in the production of secondary metabolites. In IMPORTANCE: In this study, we describe a

Indexed as

Bacterial ProteinsDrug CombinationsMacrolidesStreptomycesAcyl Coenzyme AGene Expression Regulation, BacterialMetabolic EngineeringOperonTranscription FactorsAcyl Coenzyme ABacterial ProteinsDrug CombinationsMacrolidesspinosadTranscription Factorsacetate assimilationheterologous expressionprecursor supplypropionate assimilationspinosadStreptomyces albus B4TetR family transcriptional regulator

Identifiers

PMID38904409
PMCPMC11267868

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.