Evidence map›Paper›PMID 38904271›Full record

ArticleFuture oncology (London, England)2024

Algorithms to identify radiotherapy intent in unresected non-metastatic non-small-cell lung cancer: an I-O Optimise analysis.

Eleanor Ralphs, Caroline Rault, Alan Calleja, Melinda J Daumont, John R Penrod, Matthew Thompson, Sue Cheeseman, Marta Soares

Abstract read
In one paragraph

Article in Future oncology (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eleanor RalphsReal World Solutions, IQVIA, The Point, 37 N Wharf Rd, London, W2 1AF, England.ORCID 0000-0001-7986-8205
Caroline RaultData Gnosis, 26 Rue de Leon, 35000Rennes, France.
Alan CallejaReal World Solutions, IQVIA, The Point, 37 N Wharf Rd, London, W2 1AF, England.
Melinda J DaumontWorldwide Health Economics & Outcomes Research, Bristol Myers Squibb, Av. de Finlande 4, 1420 Braine-L'Alleud, Belgium.
John R PenrodWorldwide Health Economics & Outcomes Research, Bristol Myers Squibb, 3551 Lawrenceville Rd, Princeton, NJ 08540, USA.
Matthew ThompsonREAL Oncology, Leeds Teaching Hospitals NHS Trust, Bexley Wing Cancer Centre, Beckett Street, Leeds, LS9 7TF, England.
Sue CheesemanREAL Oncology, Leeds Teaching Hospitals NHS Trust, Bexley Wing Cancer Centre, Beckett Street, Leeds, LS9 7TF, England.
Marta SoaresDepartment of Medical Oncology, Portuguese Oncology Institute of Porto (IPO-Porto), Rua Dr. António Bernardino e Almeida, 4200-072Porto, Portugal.

Funding

Bristol Myers Squibb
6 · The paper itself

Abstract

This study aimed to develop and evaluate the performance of algorithms for identifying radiotherapy (RT) treatment intent in real-world data from patients with non-metastatic non-small-cell lung cancer (NSCLC). Using data from IPO-Porto hospital (Portugal) and the REAL-Oncology database (England), three algorithms were developed based on available RT information (#1: RT duration, #2: RT duration and type, #3: RT dose) and tested versus reference datasets. Study results showed that all three algorithms had good overall accuracy (91-100%) for patients receiving RT plus systemic anticancer therapy (SACT) and algorithms #2 and #3 also had good accuracy (>99%) for patients receiving RT alone. These algorithms could help classify treatment intent in patients with NSCLC receiving RT with or without SACT in real-world settings where intent information is missing/incomplete.

Indexed as

AlgorithmsCarcinoma, Non-Small-Cell LungLung NeoplasmsAgedAged, 80 and overFemaleHumansMaleMiddle AgedNeoplasm StagingRadiotherapy DosageRadiotherapy Planning, Computer-AssistedalgorithmcurativeI-O Optimisemethodologynon-metastaticnon-small-cell lung cancerpalliativeradiotherapytreatment intent

Identifiers

PMID38904271
PMCPMC11485750

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.