Evidence map›Paper›PMID 38904250›Full record

ArticleJournal of the American Heart Association2024

Diagnostic Performance of Coronary Angiography Derived Computational Fractional Flow Reserve.

Madhurima Vardhan, Cyrus Tanade, S James Chen, Owais Mahmood, Jaidip Chakravartti, W Schuyler Jones, Andrew M Kahn, Sreekanth Vemulapalli, Manesh Patel, Jane A Leopold and 1 more

Abstract readMulticenter StudyValidation Study
In one paragraph

Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Madhurima VardhanDepartment of Biomedical Duke University Durham NC USA.ORCID 0000-0003-4019-7832
Cyrus TanadeDepartment of Biomedical Duke University Durham NC USA.ORCID 0000-0002-2395-6908
S James ChenDepartment of Medicine University of Colorado Aurora CO USA.
Owais MahmoodDepartment of Biomedical Duke University Durham NC USA.
Jaidip ChakravarttiDepartment of Medicine Duke University Durham NC USA.ORCID 0000-0001-5057-465X
W Schuyler JonesDepartment of Medicine University of Colorado Aurora CO USA.ORCID 0000-0002-7288-9596
Andrew M KahnDivision of Cardiovascular Medicine University of California San Diego La Jolla CA USA.ORCID 0000-0002-6677-4215
Sreekanth VemulapalliDepartment of Biomedical Duke University Durham NC USA.ORCID 0000-0003-1599-2957
Manesh PatelDepartment of Biomedical Duke University Durham NC USA.ORCID 0000-0002-2393-0855
Jane A LeopoldDivision of Cardiovascular Medicine Brigham and Women's Hospital Boston MA USA.ORCID 0000-0003-0598-8882
Amanda RandlesDepartment of Biomedical Duke University Durham NC USA.ORCID 0000-0001-6318-3885

Funding

Dynamic models of the cardiovascular system capturing years, rather than heartbeatsDP1AG082343 · NIA · DUKE UNIVERSITY · PI Amanda E Randles · 2022 to 2026
$5.6M
Toward coupled multiphysics models of hemodynamics on leadership systemsDP5OD019876 · OD · UNIVERSITY OF CALIF-LAWRNC LVRMR NAT LAB · PI RANDLES, AMANDA E · 2014 to 2018
$2.0M
Intergrated Endothelial Phenotyping to Redefine Pulmonary HypertensionU01HL125215 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LEOPOLD, JANE A, WAXMAN, AARON B · 2014 to 2018
$1.7M
Technology for efficient simulation of cancer cell transportU01CA253511 · NCI · DUKE UNIVERSITY · PI RANDLES, AMANDA E · 2020 to 2022
$1.1M
NCI NIH HHS U01 CA253511NHLBI NIH HHS U01 HL125215NIA NIH HHS DP1 AG082343NIH HHS DP5 OD019876
6 · The paper itself

Abstract

backgroundComputational fluid dynamics can compute fractional flow reserve (FFR) accurately. However, existing models are limited by either the intravascular hemodynamic phenomarkers that can be captured or the fidelity of geometries that can be modeled. METHODS AND

resultsThis study aimed to validate a new coronary angiography-based FFR framework, FFR

conclusionsFFR

Indexed as

Coronary AngiographyFractional Flow Reserve, MyocardialPredictive Value of TestsAgedCoronary Artery DiseaseCoronary StenosisCoronary VesselsFemaleHemodynamicsHumansMaleMiddle AgedModels, CardiovascularReproducibility of Resultscomputational fluid dynamicsfractional flow reservelongitudinal vorticity

Identifiers

PMID38904250
PMCPMC11255717

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.