Evidence map›Paper›PMID 38904243›Full record

ArticleJournal of the American Heart Association2024

Advanced Heart Failure Characteristics and Outcomes in Women and Men.

Naba Farooqui, Jill M Killian, Jamie Smith, Margaret M Redfield, Shannon M Dunlay

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Sex differences in vascular function among individuals with heart failure: a systematic review.International journal of cardiology. Heart & vasculature · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Transition to Advanced Heart Failure: From Identification to Improving Prognosis.Journal of cardiovascular development and disease · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Naba FarooquiDepartment of Internal Medicine Mayo Clinic Rochester MN USA.ORCID 0000-0002-2429-4627
Jill M KillianDepartment of Quantitative Health Sciences Mayo Clinic Rochester MN USA.ORCID 0000-0003-3906-4020
Jamie SmithRobert D. and Patricia E. Kern Center for the Science of Health Care Delivery Mayo Clinic Rochester MN USA.
Margaret M RedfieldDepartment of Cardiovascular Medicine Mayo Clinic Rochester MN USA.ORCID 0000-0002-0946-7518
Shannon M DunlayRobert D. and Patricia E. Kern Center for the Science of Health Care Delivery Mayo Clinic Rochester MN USA.ORCID 0000-0001-5145-7420

Funding

Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
NATURAL HISTORY OF PROSTATISM--THE OLMSTED COUNTY STUDYR01DK058859 · NIDDK · MAYO CLINIC ROCHESTER · PI ST SAUVER, JENNIFER LYNN · 2000 to 2010
$5.7M
Advanced Heart Failure: Epidemiology and OutcomesR01HL144529 · NHLBI · MAYO CLINIC ROCHESTER · PI DUNLAY, SHANNON MARIE · 2019 to 2023
$3.6M
Interdisciplinary Infrastructure for Aging Research: Rochester Epidemiology ProjectR33AG058738 · NIA · MAYO CLINIC ROCHESTER · PI LEBRASSEUR, NATHAN K, OLSON, JANET E · 2020 to 2022
$2.4M
NHLBI NIH HHS R01 HL144529NIA NIH HHS R01 AG034676NIA NIH HHS R33 AG058738NIDDK NIH HHS R01 DK058859
6 · The paper itself

Abstract

backgroundThe epidemiology and pathophysiology of heart failure (HF) differ in women and men. Whether these differences extend to the subgroup of patients with advanced HF is not well defined. METHODS AND

resultsThis is a retrospective cohort study of all adult Olmsted County, Minnesota residents with advanced HF (European Society of Cardiology criteria) from 2007 to 2017. Differences in survival and hospitalization risks in women and men following advanced HF development were examined using Cox proportional hazard regression and Andersen-Gill models, respectively. Of 936 individuals with advanced HF, 417 (44.6%) were women and 519 (55.4%) were men (self-reported sex). Time from development of HF to advanced HF was similar in women and men (median 3.2 versus 3.6 years). Women were older at diagnosis (mean age 79 versus 75 years), less often had coronary disease and hyperlipidemia, but more often had hypertension and depression (

conclusionsWomen more often present with advanced HF with preserved ejection fraction and men with atherosclerotic disease and advanced HF with reduced ejection fraction. Despite these differences, survival and hospitalization risks are largely comparable in women and men with advanced HF.

Indexed as

Heart FailureHospitalizationStroke VolumeAgedAged, 80 and overCause of DeathFemaleHumansMaleMiddle AgedMinnesotaPrognosisRetrospective StudiesRisk AssessmentRisk FactorsSex Factorsadvanced heart failureepidemiologymortalitysex

Identifiers

PMID38904243
PMCPMC11255701

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.