Evidence map›Paper›PMID 38903954›Full record

ReviewClinical kidney journal2024

Does online high-volume hemodiafiltration offer greater efficiency and sustainability compared with high-flux hemodialysis? A detailed simulation analysis anchored in real-world data.

Bernard Canaud, Alfred Gagel, Arne Peters, Andreas Maierhofer, Stefano Stuard

Abstract readReview
In one paragraph

Review in Clinical kidney journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. A website calculator to benchmark the carbon footprint of haemodialysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026
    Article
  8. Article
  9. The Role of Online Hemodiafiltration in Contemporary Kidney Care.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Review
  10. Review
  11. Review
  12. Article
  13. Observational
  14. Green nephrology: from evidence to action.Nature reviews. Nephrology · 2025
    Article
  15. Article
  16. Haemodiafiltration versus high-flux haemodialysis-a Consensus Statement from the EuDial Working Group of the ERA.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Article
  17. Review
  18. Review
  19. Article
  20. Green, Sustainable Nephrology: State of the Art Needs for Education and Implementation.Clinical journal of the American Society of Nephrology : CJASN · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bernard CanaudNephrology Department, Montpellier University, School of Medicine, and Foundation Ch. Mion, AIDER-Santé, Montpellier, France.ORCID https://orcid.org/0000-0001-6854-2816
Alfred GagelGlobal Research and Development, Fresenius Medical Care Deutschland GmbH, Care Enablement, Bad Homburg, Germany.
Arne PetersGlobal Research and Development, Fresenius Medical Care Deutschland GmbH, Care Enablement, Bad Homburg, Germany.
Andreas MaierhoferGlobal Research and Development, Fresenius Medical Care Deutschland GmbH, Care Enablement, Bad Homburg, Germany.
Stefano StuardClinical & Therapeutic Governance, Fresenius Medical Care, Global Medical Office, EMEA Clinical & Therapeutic Governance, Bad Homburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent findings, including the CONVINCE (comparison of high-dose HDF with high-flux HD) study report, suggest the superiority of high-volume hemodiafiltration (HDF) over high-flux hemodialysis (HD) in improving patients' outcomes. Despite positive patient outcomes, concerns have arisen about the potential negative environmental impact of high-volume HDF, as it may lead to increased water and dialysis fluid consumption and higher waste production. In this manuscript, we address the environmental impact of high-volume HDF, focusing on three key factors: water treatment consumption, dialysis fluid consumption, and solute efficiency markers of HD and HDF. By optimizing HDF prescription through adjustments in operational capabilities, while keeping a high blood flow (i.e., >350 ml/min) such as reducing the Q

Indexed as

end-stage kidney diseasegreen dialysisrenal replacement therapysustainable dialysis

Identifiers

PMID38903954
PMCPMC11187497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.