Evidence map›Paper›PMID 38903949›Full record

ArticleRespirology case reports2024

A combined small cell lung carcinoma patient with only small cell carcinoma components in mediastinal lymph node metastasis and chondrosarcoma-like components in liver metastasis.

Takako Kawaguchi, Kei Yamasaki, Saki Shigemi, Hiroki Dosaka, Riho Hirosawa, Taiga Nagasawa, Satoshi Fujimoto, Shohei Shimajiri, Kazuhiro Yatera

Abstract readCase Reports
In one paragraph

Article in Respirology case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Takako KawaguchiDepartment of Respiratory Medicine University of Occupational and Environmental Health, Japan Kitakyushu Japan.ORCID https://orcid.org/0000-0002-2289-0003
Kei YamasakiDepartment of Respiratory Medicine University of Occupational and Environmental Health, Japan Kitakyushu Japan.ORCID https://orcid.org/0000-0003-1876-3287
Saki ShigemiDepartment of Respiratory Medicine University of Occupational and Environmental Health, Japan Kitakyushu Japan.
Hiroki DosakaDepartment of Respiratory Medicine University of Occupational and Environmental Health, Japan Kitakyushu Japan.
Riho HirosawaDepartment of Respiratory Medicine University of Occupational and Environmental Health, Japan Kitakyushu Japan.
Taiga NagasawaDepartment of Respiratory Medicine University of Occupational and Environmental Health, Japan Kitakyushu Japan.
Satoshi FujimotoDepartment of Respiratory Medicine University of Occupational and Environmental Health, Japan Kitakyushu Japan.
Shohei ShimajiriDepartment of Pathology University of Occupational and Environmental Health, Japan Kitakyushu Japan.
Kazuhiro YateraDepartment of Respiratory Medicine University of Occupational and Environmental Health, Japan Kitakyushu Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 69-year-old ex-smoker Japanese man presented with a left mediastinal lymph node and left upper lobe tumour. Bronchoscopic biopsy specimens from the enlarged left mediastinal lymph node and left upper lobe tumour revealed small cell lung carcinoma (SCLC). He was treated with first-line chemotherapy with carboplatin, etoposide, and atezolizumab for four courses and subsequent atezolizumab maintenance therapy. However, his left upper lobe lung tumour only increased in size, and left upper lobectomy revealed combined SCLC (adenocarcinoma and chondrosarcoma-like features). Four months after lobectomy, liver metastasis of chondrosarcoma-like features (similar to pathological findings of the left upper lobe tumour) were observed. Combined SCLC, including sarcomatous components, is rare and poorly responds to chemotherapy. The metastases of combined SCLC in this patient were of only one type of histological component, making diagnosis and treatment difficult. If treatment for SCLC responds inadequately, considering combined SCLC and actively re-examining histological diagnosis is necessary.

Indexed as

chondrosarcoma‐like featurescombined small cell lung carcinomalobectomylymph node metastasissmall cell lung carcinoma

Identifiers

PMID38903949
PMCPMC11187537

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.