Evidence map›Paper›PMID 38903539›Full record

ArticleFrontiers in molecular biosciences2023

Are there double knots in proteins? Prediction and

Agata P Perlinska, Mai Lan Nguyen, Smita P Pilla, Emilia Staszor, Iwona Lewandowska, Agata Bernat, Elżbieta Purta, Rafal Augustyniak, Janusz M Bujnicki, Joanna I Sulkowska

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in molecular biosciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Novel Knotted Solenoid fold with order-shifted coil arrangement leads to nontrivial 3Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Agata P PerlinskaCentre of New Technologies, University of Warsaw, Warsaw, Poland.
Mai Lan NguyenCentre of New Technologies, University of Warsaw, Warsaw, Poland.
Smita P PillaCentre of New Technologies, University of Warsaw, Warsaw, Poland.
Emilia StaszorCentre of New Technologies, University of Warsaw, Warsaw, Poland.
Iwona LewandowskaCentre of New Technologies, University of Warsaw, Warsaw, Poland.
Agata BernatLaboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, Warsaw, Poland.
Elżbieta PurtaLaboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, Warsaw, Poland.
Rafal AugustyniakFaculty of Chemistry, University of Warsaw, Warsaw, Poland.
Janusz M BujnickiLaboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, Warsaw, Poland.
Joanna I SulkowskaCentre of New Technologies, University of Warsaw, Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have been aware of the existence of knotted proteins for over 30 years-but it is hard to predict what is the most complicated knot that can be formed in proteins. Here, we show new and the most complex knotted topologies recorded to date-double trefoil knots (3

Indexed as

composite knotdomainevolutionmethyltransferaseSPOUT

Identifiers

PMID38903539
PMCPMC11187310

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.