Evidence map›Paper›PMID 38903484›Full record

ArticlePulmonary circulation2024

Excess healthcare resource utilization and costs for commercially insured patients with pulmonary arterial hypertension: A real-world data analysis.

Tracey Weiss, Dena R Ramey, Ngan Pham, Nazneen Fatima Shaikh, Dajun Tian, Xiaohui Zhao, Aimee M Near, Dominik Lautsch, Steven D Nathan

Abstract read
In one paragraph

Article in Pulmonary circulation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tracey WeissMerck & Co., Inc. Rahway New Jersey USA.
Dena R RameyMerck & Co., Inc. Rahway New Jersey USA.
Ngan PhamIQVIA Inc. Durham North Carolina USA.
Nazneen Fatima ShaikhIQVIA Inc. Durham North Carolina USA.ORCID 0000-0002-4184-1610
Dajun TianIQVIA Inc. Durham North Carolina USA.
Xiaohui ZhaoIQVIA Inc. Durham North Carolina USA.
Aimee M NearIQVIA Inc. Durham North Carolina USA.
Dominik LautschMerck & Co., Inc. Rahway New Jersey USA.
Steven D NathanInova Fairfax Hospital Falls Church Virginia USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This retrospective study was conducted to evaluate all-cause healthcare resource utilization (HCRU) and costs in commercially insured patients living with pulmonary arterial hypertension (PAH) and explore end-of-life (EOL)-related HCRU and costs. Data from the IQVIA PharMetrics® Plus database (October 2014 to May 2020) were analyzed to identify adults (≥18 years) with PAH (PAH cohort) and those without PH (non-PH cohort). Patients were required to have data for ≥12 months before (baseline) and ≥6 months after (follow-up) the first observed PH diagnosis (index date) for PAH cohort or pseudo index date for non-PH cohort. A PAH EOL cohort was similarly constructed using a broader data window (October 2014 to March 2022) and ≥1 month of follow-up. Annualized all-cause HCRU and costs during follow-up were compared between PAH and non-PH cohorts after 1:1 matching on propensity scores derived from patient characteristics. EOL-related HCRU and costs were explored within 30 days and 6 months before the death date and estimated by a claims-based algorithm in PAH EOL cohort. The annual all-cause total ($183,616 vs. $20,212) and pharmacy ($115,926 vs. $7862; both

Indexed as

end‐of‐life carehealthcare costshealthcare resource utilizationmortalitypulmonary artery hypertension (PAH)

Identifiers

PMID38903484
PMCPMC11186841

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.