Evidence map›Paper›PMID 38903237›Full record

ArticleChemical science2024

Re-pairing DNA: binding of a ruthenium phi complex to a double mismatch.

Tayler D Prieto Otoya, Kane T McQuaid, Neil G Paterson, David J Cardin, Andrew Kellett, Christine J Cardin

Erratum issuedAbstract read
In one paragraph

Article in Chemical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Tayler D Prieto OtoyaDepartment of Chemistry, University of Reading Whiteknights Reading, RG6 6AD UK c.j.cardin@reading.ac.uk.
Kane T McQuaidDepartment of Chemistry, University of Reading Whiteknights Reading, RG6 6AD UK c.j.cardin@reading.ac.uk.
Neil G PatersonDiamond Light Source Ltd Harwell Science and Innovation Campus Didcot Oxfordshire OX11 0DE UK.
David J CardinDepartment of Chemistry, University of Reading Whiteknights Reading, RG6 6AD UK c.j.cardin@reading.ac.uk.
Andrew KellettSSPC, The Science Foundation Ireland Research Centre for Pharmaceuticals, School of Chemical Sciences, Dublin City University Glasnevin Dublin 9 Ireland.ORCID https://orcid.org/0000-0002-8947-1401
Christine J CardinDepartment of Chemistry, University of Reading Whiteknights Reading, RG6 6AD UK c.j.cardin@reading.ac.uk.ORCID https://orcid.org/0000-0002-2556-9995

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a crystal structure at atomic resolution (0.9 Å) of a ruthenium complex bound to a consecutive DNA double mismatch, which results in a TA basepair with flipped out thymine, together with the formation of an adenine bulge. The structure shows a form of metalloinsertion interaction of the Λ-[Ru(phen)

Identifiers

PMID38903237
PMCPMC11186304

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.