Evidence map›Paper›PMID 38903169›Full record

ArticleFrontiers in neurology2024

Paradigm shift in Parkinson's disease: using continuous telemonitoring to improve symptoms control. Results from a 2-years journey.

Spyridon Konitsiotis, Athanasia Alexoudi, Panagiotis Zikos, Christos Sidiropoulos, George Tagaris, Georgia Xiromerisiou, Konstantinos Tsamis, Nicholas Kostikis, Foivos Kanellos, Adamantios Ntanis and 2 more

Abstract read
In one paragraph

Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Spyridon KonitsiotisUniversity Hospital of Ioannina and Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.
Athanasia AlexoudiDepartment of Neurology, Neurological Institute of Athens, Athens, Greece.
Panagiotis ZikosDepartment of Neurology, 251 Hellenic Air Force Hospital, Athens, Greece.
Christos SidiropoulosDepartment of Neurology, Michigan State University, East Lansing, MI, United States.
George TagarisDepartment of Neurology, General Hospital of Athens, "Georgios Gennimatas", Athens, Greece.
Georgia XiromerisiouDepartment of Neurology, University Hospital of Larissa, Larissa, Greece.
Konstantinos TsamisDepartment of Physiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.
Nicholas KostikisPD Neurotechnology Ltd., Ioannina, Greece.
Foivos KanellosDepartment of Physiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.
Adamantios NtanisPD Neurotechnology Ltd., Ioannina, Greece.
Spyridon KontaxisPD Neurotechnology Ltd., Ioannina, Greece.
George RigasPD Neurotechnology Ltd., Ioannina, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Conventional care in Parkinson's disease (PD) faces limitations due to the significant time and location commitments needed for regular assessments, lacking quantitative measurements. Telemonitoring offers clinicians an opportunity to evaluate patient symptomatology throughout the day during activities of daily living. Methods: The progression of PD symptoms over a two-year period was investigated in patients undergoing traditional evaluation, supplemented by insights from ambulatory measurements. Physicians integrated a telemonitoring device, the PDMonitor Results: Statistical analyses examining intra-subject changes for 17 subjects revealed a significant relative decrease of -43.9% in the device-reported percentage of time spent in "OFF" state (from 36.2 to 20.3%). Following the 24-month period, the majority of the subjects improved or exhibited stable symptom manifestation. In addition to positively impacting motor symptom control, telemonitoring was found to enhance patient satisfaction about their condition, medication effectiveness, and communication with physicians. Discussion: Considering that motor function is significantly worsened over time in patients with PD, these findings suggest a positive impact of objective telemonitoring on symptoms control. Patient satisfaction regarding disease management through telemonitoring can potentially improve adherence to treatment plans. In conclusion, remote continuous monitoring paves the way for a paradigm shift in PD, focusing on actively managing and potentially improve symptoms control.

Indexed as

longitudinal analysisobjective motor assessmentpatient satisfactionreal-world datatelemonitoring

Identifiers

PMID38903169
PMCPMC11187095

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.