Evidence map›Paper›PMID 38902846›Full record

ArticleImplementation science communications2024

A mixed methods approach identifying facilitators and barriers to guide adaptations to InterCARE strategies: an integrated HIV and hypertension care model in Botswana.

Pooja Gala, Ponego Ponatshego, Laura M Bogart, Nabila Youssouf, Mareko Ramotsababa, Amelia E Van Pelt, Thato Moshomo, Evelyn Dintwa, Khumo Seipone, Maliha Ilias and 4 more

Registry-linked trialAbstract read
In one paragraph

Article in Implementation science communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05414526 (Integrating Hypertension and Cardiovascular Diseases Care Into Existing HIV Services Package in Botswana), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05414526 nacompletednot on this map

Integrating Hypertension and Cardiovascular Diseases Care Into Existing HIV Services Package in Botswana (InterCARE)

TypeinterventionalSponsorUniversity of BotswanaRan2023 to 2025Enrolled4,655ConditionsHIV Infections, HypertensionArmsInterCARE package
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Pooja Gala *Department of Medicine, NYU Langone Grossman School of Medicine, New York, NY, USA. pgala87@gmail.com.ORCID http://orcid.org/0000-0002-7505-9352
Ponego Ponatshego *Department of Internal Medicine, Faculty of Medicine, University of Botswana, Gaborone, Botswana.
Laura M BogartRAND Corporation, Santa Monica, CA, USA.
Nabila YoussoufDepartment of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.
Mareko RamotsababaGovernment of Botswana, Ministry of Health and Wellness, Gaborone, Botswana.
Amelia E Van PeltDepartment of Medical Social Sciences, Northwestern University, Chicago, IL, USA.
Thato MoshomoDepartment of Internal Medicine, Faculty of Medicine, University of Botswana, Gaborone, Botswana.
Evelyn DintwaGovernment of Botswana, Ministry of Health and Wellness, Gaborone, Botswana.
Khumo SeiponeGovernment of Botswana, Ministry of Health and Wellness, Gaborone, Botswana.
Maliha IliasCenter for Translation Research and Implementation Science, Department of Health and Human Services, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Veronica TonweCenter for Translation Research and Implementation Science, Department of Health and Human Services, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Tendani Gaolathe *Department of Internal Medicine, Faculty of Medicine, University of Botswana, Gaborone, Botswana.
Lisa R Hirschhorn *Department of Medical Social Sciences, Northwestern University, Chicago, IL, USA.
Mosepele Mosepele *Department of Internal Medicine, Faculty of Medicine, University of Botswana, Gaborone, Botswana.

Funding

UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Sung-Jae Lee · 1997 to 2026
$53.5M
Supplement: Implementation Research Strategies for Heart, Lung, and Blood Co-morbidities in People Living with HIV - Research Coordinating CenterU24HL154426 · NHLBI · WASHINGTON UNIVERSITY · PI DAVILA-ROMAN, VICTOR G., GENG, ELVIN H. · 2020 to 2024
$9.5M
Integrating Hypertension and Cardiovascular Disease Care into Existing HIV Service Package in Botswana (InterCARE)UH3HL154499 · NHLBI · UNIVERSITY OF BOTSWANA · PI GAOLATHE, TENDANI, JAFFAR, SHABBAR · 2022 to 2024
$2.1M
Integrating Hypertension and Cardiovascular Disease Care into Existing HIV Service Package in Botswana (InterCARE)UG3HL154499 · NHLBI · UNIVERSITY OF BOTSWANA · PI GAOLATHE, TENDANI, MOSEPELE, MOSEPELE · 2020 to 2021
$1.4M
NHLBI Division of Intramural Research U24HL154426NHLBI Division of Intramural Research UG3HL154499NHLBI NIH HHS UG3 HL154499NHLBI NIH HHS UH3 HL154499NIMH NIH HHS P30 MH058107
6 · The paper itself

Abstract

backgroundBotswana serves as a model of success for HIV with 95% of people living with HIV (PLWH) virally suppressed. Yet, only 19% of PLWH and hypertension have controlled blood pressure. To address this gap, InterCARE, a care model that integrates HIV and hypertension care through a) provider training; b) adapted electronic health record; and c) treatment partners (peer support), was designed. This study presents results from our baseline assessment of the determinants and factors used to guide adaptations to InterCARE implementation strategies prior to a hybrid type 2 effectiveness-implementation study.

methodsThis study employed a convergent mixed methods design across two clinics (one rural, one urban) to collect quantitative and qualitative data through facility assessments, 100 stakeholder surveys (20 each PLWH and hypertension, existing HIV treatment partners, clinical healthcare providers (HCPs), and 40 community leaders) and ten stakeholder key informative interviews (KIIs). Data were analyzed using descriptive statistics and deductive qualitative analysis organized by the Consolidated Framework for Implementation Research (CFIR) and compared to identify areas of convergence and divergence.

resultsAlthough 90.3% of 290 PLWH and hypertension at the clinics were taking antihypertensive medications, 52.8% had uncontrolled blood pressure. Results from facility assessments, surveys, and KIIs identified key determinants in the CFIR innovation and inner setting domains. Most stakeholders (> 85%) agreed that InterCARE was adaptable, compatible and would be successful at improving blood pressure control in PLWH and hypertension. HCPs agreed that there were insufficient resources (40%), consistent with facility assessments and KIIs which identified limited staffing, inconsistent electricity, and a lack of supplies as key barriers. Adaptations to InterCARE included a task-sharing strategy and expanded treatment partner training and support.

conclusionsIntegrating hypertension services into HIV clinics was perceived as more advantageous for PLWH than the current model of hypertension care delivered outside of HIV clinics. Identified barriers were used to adapt InterCARE implementation strategies for more effective intervention delivery.

trial registrationClinicalTrials.gov, ClinicalTrials.gov Identifier: NCT05414526 . Registered 18 May 2022 - Retrospectively registered.

Indexed as

BotswanaHIVHypertensionImplementation scienceIntegrated careLow- and middle- income countries

Identifiers

PMID38902846
PMCPMC11188218

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.