Evidence map›Paper›PMID 38902756›Full record

ArticleBiomedical engineering online2024

Diurnal variation of heart rate variability in individuals with spinal cord injury.

Jittima Saengsuwan, Arphatsorn Ruangsuphaphichat, Lars Brockmann, Patpiya Sirasaporn, Nuttaset Manimmanakorn, Kenneth J Hunt

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In one paragraph

Article in Biomedical engineering online, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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  4. Review
4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jittima SaengsuwanDepartment of Rehabilitation Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand. sjittima@kku.ac.th.
Arphatsorn RuangsuphaphichatDepartment of Rehabilitation Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Lars BrockmannThe Laboratory for Rehabilitation Engineering, Institute for Human Centred Engineering, Bern University of Applied Sciences, Biel, Switzerland.
Patpiya SirasapornDepartment of Rehabilitation Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Nuttaset ManimmanakornDepartment of Rehabilitation Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Kenneth J HuntThe Laboratory for Rehabilitation Engineering, Institute for Human Centred Engineering, Bern University of Applied Sciences, Biel, Switzerland.

Funding

Faculty of medicine, Khon Kaen university IN63106Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 320030-185351
6 · The paper itself

Abstract

backgroundHeart rate variability (HRV) may provide objective information about cardiogenic autonomic balance in individuals with spinal cord injury (SCI). The aim of this study was to characterize the diurnal variation of HRV in individuals with SCI at lesion level T6 and above and lesion level below T6.

methodsThis was a retrospective analysis of a prior cross-sectional study. Individuals with chronic SCI underwent 24 h recording of the time between consecutive R waves (RR interval) to derive parameters of HRV as follows: standard deviation of all normal-to-normal R-R intervals (SDNN) and square root of the mean of the squared differences between successive R-R intervals (RMSSD) (time domain); and high frequency power (HF), low-frequency power (LF), very low frequency power (VLF), ultra-low frequency power (ULF) and total power (TP) (frequency domain). Changes in the magnitude of HRV outcomes over the 24 h period were investigated using a novel multi-component cosinor model constrained to the form of a three-harmonic Fourier series.

resultsParticipants were grouped as lesion level T6 and above (n = 22) or below T6 (n = 36). Most of them were male (n = 40, 69%) and the median age (interquartile range) was 50.5 (28) years. Both groups exhibited similar diurnal patterns in most HRV metrics. The lowest values occurred in the late afternoon (4-6 pm) and gradually increased, peaking around midnight to early morning (1-6 am). Exceptions included RMSSD, which peaked before midnight, and ULF, which showed a double peak pattern that peaked from 11 am to 1 pm and 4-6 am in participants with lesion level at T6 and above. The HRV values in participants with lesion level T6 and above were generally lower than participants with lesion level below T6, except for peak values of RMSSD, HF and LF.

conclusionThis study demonstrated substantial diurnal variation of HRV in participants with SCI in both groups of participants. In clinical and research settings, diurnal variations in HRV must be taken into consideration.

Indexed as

Circadian RhythmHeart RateSpinal Cord InjuriesAdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedRetrospective StudiesAutonomic dysreflexiaCosinor modelDiurnal variationHeart rate variabilitySCISpinal cord injury

Identifiers

PMID38902756
PMCPMC11188279

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