Evidence map›Paper›PMID 38902740›Full record

ArticleAnnals of clinical microbiology and antimicrobials2024

Successful management of chromoblastomycosis utilizing conventional antifungal agents and imiquimod therapy.

Jinjin Zheng, Shougang Liu, Zhenmou Xie, Yangxia Chen, Liyan Xi, Hongfang Liu, Yinghui Liu

Abstract readCase Reports
In one paragraph

Article in Annals of clinical microbiology and antimicrobials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jinjin ZhengDepartment of Dermatology, Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.
Shougang LiuDepartment of Dermatology, Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.
Zhenmou XieDepartment of Dermatology, Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.
Yangxia ChenDepartment of Dermatology, Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.
Liyan XiDepartment of Dermatology, Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.
Hongfang LiuDepartment of Dermatology, Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China. sunflower1977@126.com.
Yinghui LiuDepartment of Dermatology, Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China. 898020002@qq.com.

Funding

National Nature Science Foundation of China 80902042
6 · The paper itself

Abstract

Chromoblastomycosis (CBM), a chronic fungal infection affecting the skin and subcutaneous tissues, is predominantly caused by dematiaceous fungi in tropical and subtropical areas. Characteristically, CBM presents as plaques and nodules, often leading to scarring post-healing. Besides traditional diagnostic methods such as fungal microscopy, culture, and histopathology, dermatoscopy and reflectance confocal microscopy can aid in diagnosis. The treatment of CBM is an extended and protracted process. Imiquimod, acting as an immune response modifier, boosts the host's immune response against CBM, and controls scar hyperplasia, thereby reducing the treatment duration. We present a case of CBM in Guangdong with characteristic reflectance confocal microscopy manifestations, effectively managed through a combination of itraconazole, terbinafine, and imiquimod, shedding light on novel strategies for managing this challenging condition.

Indexed as

Antifungal AgentsChromoblastomycosisImiquimodItraconazoleTerbinafineHumansMaleMicroscopy, ConfocalMiddle AgedSkinTreatment OutcomeAntifungal AgentsImiquimodItraconazoleTerbinafineChromoblastomycosisImiquimodReflectance confocal microscopyTreatment

Identifiers

PMID38902740
PMCPMC11191280

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.